ArticleBrain and behavior2025
Different Brain Network Connectomic Relationships Subserve Hand Dexterity During Task Versus Resting States in People with Brain Tumors.
Article in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Changes in Somatomotor Network Connectivity Differentiate Better Versus Worse Recovery of Hand Dexterity After Brain Tumor Surgery: A Cohort Study.Neural plasticity · 2026Article
- Different Brain Network Connectomic Relationships Subserve Hand Dexterity During Task Versus Resting States in People with Brain Tumors.Brain and behavior · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
purposeThe purpose of this study was to explore different brain network connectomic relationships subserving hand dexterity in patients with contrast-enhancing brain tumors during task and resting states.
methodWe measured hand dexterity, resting state functional connectivity, and task-based functional connectivity in 21 participants with newly diagnosed brain tumors. Hand dexterity was measured using the 9-hole peg test (9HPT), and patient-reported outcomes were assessed with the Duroz Hand Index (DHI).
findingsWe discovered the following: (1) The inability to complete dexterous tasks is most associated with low somatomotor-basal ganglia network connectivity during rest but high somatomotor-basal ganglia network connectivity during tasks; (2) in the subgroup of better dexterous performers, resting somatomotor-salience connectivity is higher in people with poor dexterity-a relationship that holds true in healthy adult subjects from the Human Connectome Project (HCP), suggesting it has fundamental importance; and (3) connectomic measurements were stronger predictors of dexterous performance than classical variables of tumor (i.e., size, grade, or anatomical location).
conclusionsThese data suggest that connectomic correlates of dexterity are different in resting and task-based states. Additionally, our data suggest a threshold level of somatomotor-to-basal ganglia connectivity is required to accomplish dexterous movements, and, in the cases of appropriately preserved somatomotor-to-basal ganglia connectivity, salience-somatomotor connectivity then becomes the dominant connection facilitating performance in a hierarchical fashion. These findings have fundamental implications for both surgical planning and neuromodulation-based rehabilitation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.