ArticleRenal failure2025
Renal interstitial infiltration by non-Hodgkin lymphoma: clinicopathological features, outcomes, and prognostic markers from a Chinese biopsy cohort.
Article in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Renal involvement by non-Hodgkin lymphoma (NHL) is under-recognized and often misdiagnosed as interstitial nephritis. Kidney biopsy remains the gold standard for confirming lymphoma interstitial infiltration. Currently, the histopathological characteristics of lymphoma-related renal interstitial infiltration and their relationship with clinical prognosis remain unclear. We retrospectively analyzed 36 biopsy-proven cases to characterize clinicopathological features, prognostic markers such as tubular basement membrane (TBM) deposits and patient outcomes. Clinicopathological data were collected at the time of kidney biopsy. The cohort included 21 males and 15 females, with a median age of 65 years (range: 19-84). Among them, 26 had indolent B-cell NHL, seven had aggressive B-cell NHL, and three had T-cell NHL. In indolent B-cell NHL, lymphoma infiltration ranged from 10 to 90%. Glomerular lesions were observed in 23 patients (23/26, 88.5%). TBM deposits were found by electron microscopy in four patients. Notably, TBM immune deposits were associated with worse kidney outcomes (
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