ArticleCureus2025
Living Young With Lupus: A Case Report on the Challenges of Multi-System Disease in a Young Adult.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Systemic erythematosus lupus (SLE) is a multisystem autoimmune disease that can present aggressively within young people. The presence of severe multi-organ disease poses multiple challenges including physical, psycho-social, and, in this case, medico-legal considerations. We present the case of a young person's journey in navigating these complexities. A 16-year-old girl, whilst on holiday abroad, presented with polyarthralgia, weight loss, severe fatigue and lower limb myalgia. Immunological markers revealed high titres of antinuclear antibody (ANA), anti-double-stranded DNA (anti-dsDNA) and anti-Smith (anti-Sm) antibodies, confirming a diagnosis of SLE. On return to the United Kingdom (UK), she developed recurrent pericardial effusion, pleural effusion and suspected lupus nephritis ensued after difficulties with treatment adherence and declining of renal biopsy. This case explores how personal autonomy, psychosocial health and treatment adherence intersect to impact disease progression and patient outcome. Ultimately, this case highlights the importance of utilising a cross-specialty approach and seeking governance support early for preparedness in acute situations and support complex decision-making. This must be balanced with careful planning to empower young people with SLE to take an active role in their condition, which can be achieved with utilisation of rheumatology transition clinics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.