Evidence map›Paper›PMID 41250748›Full record

ArticleEcology and evolution2025

Alternative Splicing and Gene Expression Variation Underlie Population and Life History Differences in an Amphibian.

Juntao Hu, Xingyue Ren, Rowan D H Barrett, Eman Samma, Mikolaj Sulkowski, Steven P Brady

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ecology and evolution, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juntao HuMinistry of Education Key Laboratory for Biodiversity Science and Ecological Engineering, Center for Evolutionary Biology, School of Life Sciences, Institute of Biodiversity Science Fudan University Shanghai People's Republic of China.
Xingyue RenMinistry of Education Key Laboratory for Biodiversity Science and Ecological Engineering, Center for Evolutionary Biology, School of Life Sciences, Institute of Biodiversity Science Fudan University Shanghai People's Republic of China.
Rowan D H BarrettDepartment of Biology McGill University Montreal Quebec Canada.
Eman SammaBiology Department Southern Connecticut State University New Haven Connecticut USA.
Mikolaj SulkowskiBiology Department Southern Connecticut State University New Haven Connecticut USA.
Steven P BradyBiology Department Southern Connecticut State University New Haven Connecticut USA.ORCID https://orcid.org/0000-0001-6119-1363

Funding

Investigating the function of localized BMP signaling at neuromuscular synapsesR15NS116630 · NINDS · SOUTHERN CONNECTICUT STATE UNIVERSITY · PI SULKOWSKI, MIKOLAJ · 2021 to 2021
$378k
NINDS NIH HHS R15 NS116630
6 · The paper itself

Abstract

Phenotypic variation is common across life history and among populations occupying different environments, yet the molecular mechanisms underlying these axes of divergence remain poorly understood. Much work has focused on gene expression as a link between genetic variation, environmental variation, and phenotypes, but post-transcriptional processes such as alternative splicing-which affect how transcripts are assembled rather than how much of a transcript is produced-are increasingly recognized as additional modulators of plasticity and adaptation. Here, we examined gene expression and alternative splicing together in the wood frog (

Indexed as

alternative splicinggene expressionlocal adaptationmaladaptationpopulation divergence

Identifiers

PMID41250748
PMCPMC12620059

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.