ReviewCureus2025
Modern Surgical Site Infection Prevention: Evidence, Gaps, and Future Directions.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Rethinking Preoperative MRSA/MSSA Screening Through Molecular Triage.Diagnostics (Basel, Switzerland) · 2026Review
- MonocrylMedical sciences (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Surgical site infections (SSIs) remain among the most consequential and costly complications in surgery. Their persistence reflects the expanding threat of multidrug-resistant (MDR) organisms and the practical limits of even increasingly data-driven, systems-level prevention programs. Contemporary prevention is multimodal across the perioperative pathway. Preoperatively, patient optimization is central, and foundational measures include alcohol-based skin antisepsis, nutritional support, smoking cessation, and strict glycemic control. Intraoperatively, the emphasis shifts to technical precision and physiologic stability, including gentle tissue handling, maintenance of normothermia, appropriate oxygenation, and disciplined operating-room traffic. In parallel, material science and precision medicine are reshaping the armamentarium: antimicrobial sutures and surface coatings, host-directed immunomodulation, and personalized, risk-adapted strategies offer targeted protection. This narrative review synthesizes current evidence across these domains. We aim to clarify which measures carry the strongest support, identify persistent gaps and implementation challenges, and outline priorities for future research and practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.