ArticleMedical science monitor : international medical journal of experimental and clinical research2025
Predictive Value of IBI for In-Hospital Death in Elderly Patients with Non-ST-Segment Elevation Myocardial Infarction.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND Non-ST-segment elevation myocardial infarction (NSTEMI) has a with high incidence rate and a high mortality rate in elderly patients, and inflammation plays an important role. As a useful inflammatory marker, the relationship between the inflammatory burden index (IBI) and in-hospital death of elderly patients with NSTEMI remains unclear. The aim of this study was to investigate the predictive value of IBI for in-hospital death in elderly patients with NSTEMI. MATERIAL AND METHODS This single-center study retrospectively enrolled patients diagnosed with NSTEMI between February 2021 and February 2025. All patients were ≥75 years old and did not receive percutaneous coronary intervention (PCI) treatment during hospitalization. Patients were divided into 2 groups according to whether cardiogenic death occurred during hospitalization. IBI was calculated as the product of C-reactive protein and the neutrophil-to-lymphocyte ratio. RESULTS This study enrolled a total of 418 patients, with a mean age of 79.60±3.67 years. During the hospitalization period, cardiogenic death occurred in 43 (10.3%) patients. After adjusting for possible confounding factors, multivariate logistic regression analysis showed that IBI (OR=2.22, 95% CI: 1.64-3.00) was an independent risk factor for in-hospital death in elderly patients with NSTEMI. Restricted cubic spline suggested a non-linear dose-response relationship between IBI and in-hospital death. The results of ROC showed that the area under the curve of IBI was 0.760. CONCLUSIONS In elderly patients with NSTEMI, IBI demonstrated an independent association with in-hospital mortality, with modest discriminatory performance. There is a non-linear dose-response relationship between IBI and in-hospital death in elderly patients with NSTEMI.
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