Evidence map›Paper›PMID 41250535›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2025

[Peak growth hormone and insulin-like growth factor 1 levels in girls with isolated premature thelarche and their predictive value for central precocious puberty].

Jie Chen, Kun-Di Wang, Rong Huang, Shu-Fang Liu, Qi Yang, Li Yang

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

6 authors.

Jie ChenDepartment of Pediatrics, Xinjiang Production and Construction Corps Hospital, Urumqi 830002, China.
Kun-Di WangDepartment of Pediatrics, Xinjiang Production and Construction Corps Hospital, Urumqi 830002, China.
Rong Huang
Shu-Fang LiuDepartment of Pediatrics, Xinjiang Production and Construction Corps Hospital, Urumqi 830002, China.
Qi Yang
Li Yang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo compare serum insulin-like growth factor 1 (IGF-1) and peak growth hormone (GH) levels between girls with isolated premature thelarche (IPT) and central precocious puberty (CPP), to construct a prediction model for progression from IPT to CPP, and to assess its diagnostic value.

methodsGirls diagnosed with IPT (

resultsIGF-1 and peak GH were higher in the CPP group than in the IPT group (

conclusionsPeak GH and IGF-1 are closely associated with progression from IPT to CPP in girls. A clinical prediction model incorporating peak GH and IGF-1 can improve prediction of progression to CPP and yield higher net benefit.

Indexed as

Human Growth HormoneInsulin-Like Growth Factor IPuberty, PrecociousChildChild, PreschoolFemaleHumansLogistic ModelsPredictive Value of TestsRetrospective StudiesHuman Growth HormoneInsulin-Like Growth Factor ICentral precocious pubertyGirlGrowth hormoneInsulin-like growth factor 1Isolated premature thelarchePredictive model

Identifiers

PMID41250535
PMCPMC12688195

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.