Evidence map›Paper›PMID 41250531›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2025

[Risk factors for white matter damage in preterm infants with necrotizing enterocolitis].

Xin Xu, Si-Rui Wang, Peng Zhang, Guo-Qiang Cheng

Abstract readEnglish Abstract
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xin XuDepartment of Neonatology, Children's Hospital of Fudan University, Shanghai 201102, China.
Si-Rui WangDepartment of Neonatology, Children's Hospital of Fudan University, Shanghai 201102, China.
Peng Zhang
Guo-Qiang Cheng

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the risk factors for white matter damage (WMD) in preterm infants with necrotizing enterocolitis (NEC).

methodsA retrospective analysis was conducted on the clinical data of 249 preterm infants with NEC admitted to Children's Hospital of Fudan University between January 2021 and December 2023. Based on brain magnetic resonance imaging (MRI) white matter scores, the infants were categorized into a WMD group (≥7 points) and a non-injury group (<7 points). A multivariable logistic regression analysis was performed to identify risk factors for WMD.

resultsCompared with the non-injury group, the WMD group had significantly higher rates of Gram-negative bacterial infection (43.1% vs 28.2%), surgical treatment (47.2% vs 23.2%), and moderate-to-severe abnormalities on video electroencephalography (VEEG) (51.4% vs 11.9%) (all

conclusionsSurgical treatment, prolonged hospitalization, and moderate-to-severe VEEG abnormalities are independent risk factors for WMD in preterm infants with NEC, providing a basis for early clinical identification and intervention to improve neurological outcomes.

Indexed as

Enterocolitis, NecrotizingWhite MatterFemaleHumansInfant, NewbornInfant, PrematureLogistic ModelsMagnetic Resonance ImagingMaleRetrospective StudiesRisk FactorsMagnetic resonance imagingNecrotizing enterocolitisPreterm infantRisk factorWhite matter damage

Identifiers

PMID41250531
PMCPMC12688190

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