Evidence map›Paper›PMID 41250213›Full record

Observational studyCritical care (London, England)2025

Timing of ceiling lift-assisted out-of-bed sitting training and outcomes in critically ill patients: a prospective cohort study.

Zhengyong Hu, Yuwen Chen, Liang Xu, Lanqi Guo, Yong Li, Min Mo, Jingyuan Xu, Xiaoqing Li, Yufen Zhu, Xiang Hong and 2 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Critical care (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Zhengyong HuDepartment of Rehabilitation Medicine, Zhongda Hospital, Southeast University, Nanjing, 210009, Jiangsu, China.
Yuwen ChenDepartment of Rehabilitation Medicine, Zhongda Hospital, Southeast University, Nanjing, 210009, Jiangsu, China.
Liang XuDepartment of Rehabilitation Medicine, Zhongda Hospital, Southeast University, Nanjing, 210009, Jiangsu, China.
Lanqi GuoJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Trauma Center, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Yong LiThe First People's Hospital of Lianyungang, The Lianyungang Clinical College of Nanjing Medical University, The First Affiliated Hospital of Kangda College of Nanjing Medical University, The Affiliated Lianyungang Hospital of Xuzhou Medical University, Lianyungang, 222000, Jiangsu, China.
Min MoJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Trauma Center, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Jingyuan XuJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Trauma Center, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Xiaoqing LiJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Trauma Center, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Yufen ZhuJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Trauma Center, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China.
Xiang HongDepartment of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, 210009, Jiangsu, China.
Hongxing WangDepartment of Rehabilitation Medicine, Zhongda Hospital, Southeast University, Nanjing, 210009, Jiangsu, China.
Songqiao LiuJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, Trauma Center, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, 210009, Jiangsu, China. liusongqiao@ymail.com.

Funding

Nanjing Health Science and Technology Development Special Fund Project No. YKK23275National Natural Science Foundation of China No. 82472202
6 · The paper itself

Abstract

backgroundEarly mobilization is widely adopted in modern ICU practice, but evidence regarding the safety and clinical outcomes of early ceiling lift-assisted out-of-bed sitting training (OBST) remains limited.

methodsThis prospective observational cohort study was conducted in the ICU of Zhongda Hospital, Nanjing, China. Adults aged 18–80 years who underwent ceiling lift–assisted OBST and had an ICU stay of ≥ 24 h, were categorized by the timing of their first OBST session as early (≤ 72 h after ICU admission) or late (> 72 h after ICU admission). Trained personnel prospectively collected data from electronic health records, session logs, and telephone interviews as appropriate. Propensity score matching was used to adjust for potential confounders. The primary outcome was the rate of potential safety events per OBST session; non-inferiority of early OBST was prespecified with a 2% absolute margin.

resultsBetween February 1, 2023, and May 17, 2024, 584 patients were screened, and 396 were enrolled (early: n = 136; late: n = 260). After 1:1 propensity score matching, 125 patients remained in each matched group. Potential safety event rates were 0.36% (early) vs 0.99% (late) per session (risk difference: − 0.63%; 95% CI: − 1.51% to 0.25%). The upper limit of the 95% CI was below the 2% noninferiority margin. Early OBST was associated with greater improvement in FSS-ICU scores (mean difference: 1.31 points, P = 0.020), shorter ICU length of stay (mean difference: − 2.75 days, P < 0.001), and fewer OBST sessions (mean difference: − 2.02 sessions, P < 0.001). Follow-up for 28-day post-ICU mortality was completed in 96.4% of patients.

conclusionsEarly ceiling lift–assisted OBST was associated not with increased safety event rates but with improved functional outcomes and a shorter ICU stay. These findings suggest that early OBST can be used safely in ICU mobilization and warrant evaluation in randomized controlled trials.

trial registrationChinese Clinical Trial Registry (ChiCTR), ChiCTR2200066701. Registered on 14 December 2022.

Indexed as

Critical IllnessEarly AmbulationSitting PositionAdolescentAdultAgedAged, 80 and overChinaCohort StudiesFemaleHumansIntensive Care UnitsLength of StayMaleMiddle AgedPropensity ScoreCeiling liftCritically ill patientsMobilizationOut-of-bed sitting trainingPotential safety events

Identifiers

PMID41250213
PMCPMC12625302

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.