SynthesisEuropean journal of medical research2025
Impact of renal impairment on outcomes of intracerebral hemorrhage: a systematic review and meta-analysis.
Synthesis in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk stratification and prognostic outcomes in intracerebral hemorrhage among patients with chronic kidney disease: a population-oriented meta-analysis.Frontiers in medicine · 2026Pooled it
- Admission eGFR as a Marker of Systemic Vulnerability in Patients with Spontaneous Intracerebral Hemorrhage: Impact of Premorbid Disability and Acute Kidney Injury on Outcomes.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic kidney disease (CKD) is linked to a number of cardiovascular complications, including intracerebral hemorrhage (ICH). However, the potential association between CKD and the outcomes of ICH are still inconclusive. This review aimed to clarify the relationship between CKD and ICH outcomes, such as mortality, functional disability, and length of hospitalization.
methodsA comprehensive literature search was done in MEDLINE, Scopus, and Cochrane Central Register of Controlled Trials (CENTRAL), Google Scholar, EMBASE databases from inception until November 2023. Observational studies examining adult ICH patients with CKD were included. Risk of bias was evaluated using Newcastle-Ottawa Scale, and data synthesis was performed by random-effects meta-analysis.
resultsTwenty studies were included, encompassing a broad range of CKD and ICH patients. The meta-analysis demonstrated a significant association between CKD and adverse ICH outcomes. CKD patients had significantly higher mortality rates (pooled OR = 2.21; 95%CI 1.88-2.59; I
conclusionOur findings showed that CKD was linked to higher rates of mortality, and functional disability in patients with ICH, and was associated with extended hospitalization. Our results underscore the need for a comprehensive, multidisciplinary approach to managing this complex patient population. Further research should elucidate the underlying mechanisms of this association and inform strategies for improving patient outcomes. The integration of nephrological and neurological care may significantly benefit the management and prognosis of ICH in patients with CKD.
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