Evidence map›Paper›PMID 41250164›Full record

Trial reportTrials2025

Effects of narrative nursing on delirium and outcomes in mechanically ventilated ICU patients: a randomized trial.

Yan Lei, Yun Song, Yongxing Wang, Jing Liu, Dan Liu, Chenjing Shi, Hua He, Binghua Zhang, Yue Cai

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yan Lei *Department of Respiration, The Fourth Military Medical University Xijing Hospital, The 986Th Hospital, Xian, 710054, China.
Yun Song *General Surgery Ward 2 District, The Fourth Military Medical University Xijing Hospital, The 986Th Hospital, Xian, 710054, China.
Yongxing Wang *Department of Critical Care Medicine, The Fourth Military Medical University Xijing Hospital, The 986Th Hospital, Xian, 710054, China.
Jing LiuDepartment of Respiration, The Fourth Military Medical University Xijing Hospital, The 986Th Hospital, Xian, 710054, China.
Dan LiuDepartment of Respiration, The Fourth Military Medical University Xijing Hospital, The 986Th Hospital, Xian, 710054, China.
Chenjing ShiDepartment of Respiration, The Fourth Military Medical University Xijing Hospital, The 986Th Hospital, Xian, 710054, China.
Hua HeDepartment of Respiration, The Fourth Military Medical University Xijing Hospital, The 986Th Hospital, Xian, 710054, China.
Binghua ZhangDepartment of Respiration, The Fourth Military Medical University Xijing Hospital, The 986Th Hospital, Xian, 710054, China. reszbh986@163.com.
Yue CaiDepartment of Cardiology, The First Affiliated Hospital of Air Force Medical University, Xian, 710032, China. 15332418996@163.com.

Funding

the National Natural Fund NSF81970383
6 · The paper itself

Abstract

objectiveTo evaluate whether a structured narrative nursing intervention reduces the incidence and duration of delirium, improves clinical outcomes, and increases patient satisfaction in mechanically ventilated intensive care unit (ICU) patients.

methodsIn this single-center, randomized controlled trial, 88 mechanically ventilated ICU patients were randomly assigned, by a computer-generated sequence, to an intervention group (n = 44) or a control group (n = 44). The control group received standard ICU care. In addition to standard care, the intervention group received a daily 30-min structured narrative nursing session throughout the period of mechanical ventilation. The intervention comprised four components: externalization of problems, deconstruction, re-authoring, and witnessing. The primary outcome was delirium incidence, assessed with the Confusion Assessment Method for the ICU (CAM-ICU). Secondary outcomes included ICU length of stay, duration of mechanical ventilation, ICU mortality, patient satisfaction, and Acute Physiology and Chronic Health Evaluation II (APACHE II) score. As this study evaluated standard nursing care interventions without the use of investigational drugs or devices, prospective clinical trial registration was not required.

resultsThe overall incidence of delirium was significantly lower in the intervention group compared with the control group (34.1% vs. 63.6%, P < 0.001), with the most pronounced reduction observed in hypoactive delirium (20.5% vs. 40.9%, P = 0.02). Both the onset and duration of delirium were markedly shortened in the intervention group (P < 0.05). Compared with controls, patients receiving narrative nursing exhibited shorter ICU stays and fewer days on mechanical ventilation (P < 0.05), a reduced ICU mortality rate (6.8% vs. 22.7%, P = 0.035), lower SOFA scores (P = 0.019), and significantly higher nursing satisfaction (P < 0.001). Multivariable logistic regression identified narrative nursing as an independent protective factor against delirium (OR = 0.27, 95% CI: 0.10-0.70, P = 0.008). Subgroup analysis by age demonstrated that the protective effect was particularly evident in older patients (≥65 years), where the intervention markedly reduced the risk of delirium (OR = 0.13, 95% CI: 0.04-0.48, P = 0.002). In contrast, among younger patients, the main benefit was reflected in improved satisfaction with nursing care.

conclusionA structured narrative nursing intervention reduced the incidence and duration of delirium among mechanically ventilated ICU patients, improved selected clinical outcomes, and increased patient satisfaction. Limitations include the single-center design, modest sample size, and limited blinding, which may introduce bias. Multicenter, adequately powered, prospectively registered randomized trials are warranted to confirm these findings.

Indexed as

Critical Care NursingDeliriumIntensive Care UnitsNarrationRespiration, ArtificialAgedAPACHEFemaleHospital MortalityHumansIncidenceLength of StayMaleMiddle AgedPatient SatisfactionTime FactorsClinical outcomesDeliriumICUMechanical ventilationNarrative nursingNursing satisfaction

Identifiers

PMID41250164
PMCPMC12625294

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.