ArticleBMC pregnancy and childbirth2025
The effect of surgically-induced ampullary hydrosalpinx after salpingostomy for ectopic pregnancy on IVF/ICSI Outcomes.
Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundSurgically-induced ampullary hydrosalpinx is a potential complication following salpingostomy for ectopic pregnancy, yet its impact on subsequent IVF/ICSI outcomes remains unclear. This study aimed to investigate the efficacy of surgical correction of this specific hydrosalpinx type.
methodsThis retrospective cohort study analyzed 374 patients diagnosed with ampullary hydrosalpinx via hysterosalpingography or hysterosalpingo-contrast sonography after previous salpingostomy for tubal ectopic pregnancy. Participants were divided into a surgically treated group (n = 86) and an untreated group (n = 74) for frozen embryo transfer (FET) cycles, with additional fresh transfer cycle data included. Primary outcomes included implantation rate, clinical pregnancy rate, live birth rate, and miscarriage rate.
resultsIn frozen embryo transfer cycles, the surgically treated group was linked to a markedly lower incidence of early miscarriage compared to the untreated group (5.6% vs. 20.0%, P = 0.028), with an adjusted odds ratio of 0.24 (95% CI: 0.06-0.93, P = 0.039). The surgically treated group also exhibited numerically higher rates of clinical pregnancy (62.8% vs. 60.8%) and live birth rates (58.1% vs. 47.3%), though these differences did not reach statistical significance. In fresh embryo transfer cycles, no significant differences in reproductive outcomes were observed between the two groups.
conclusionSurgical management of ampullary hydrosalpinx prior to frozen embryo transfer is associated with a significantly reduced risk of early miscarriage. These findings support considering surgical intervention, particularly salpingectomy, for patients with iatrogenic hydrosalpinx prior to FET to improve reproductive outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.