ArticleBMC public health2025
NYHA classification and quality of life in older heart failure inpatients: the mediation effects of social frailty and physical frailty.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of Nurse-Led Interventions on Quality of Life and Self-Care Among Patients With Heart Failure: A Systematic Review.Scandinavian journal of caring sciences · 2026Pooled it
- Health-Related Quality of Life and Associated Factors in Patients with Heart Failure Across Three Ejection Fraction Categories: A Two-Center Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Clinical and Comorbidity-Related Factors Associated with Health-Related Quality of Life in Patients with Heart Failure: A Cross-Sectional Study.Journal of clinical medicine · 2026Article
- Health-related quality of life and six-month hospitalization in older outpatients with heart failure with reduced ejection fraction: a prospective observational study.Health and quality of life outcomes · 2026Observational
- Observational
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study explores the health-related quality of life (QOL) level and its factors that influence older heart failure inpatients. It also examines the correlation between social frailty, physical frailty, emotional QOL, and physical QOL and verifies the multiple mediating roles of social frailty and physical frailty in the relationship.
methodsThis cross-sectional study collected four hundred twenty-four questionnaires from Northeast, Northwest, and South China. The research assessment tools include the FRAIL scale (physical frailty), the MLHFQ (emotional and physical QOL), and the HALFT scale (social frailty). Data analysis was performed using multiple regression analysis and the SPSS PROCESS Macro plug-in Model 4.
resultsAge (B = 0.297, p < 0.001), monthly income (B=-3.087, p < 0.001), and marital status (B=-2.295, p = 0.027) were factors influencing emotional QOL in older heart failure inpatients. Moreover, NYHA classes (B = 3.894, p < 0.001), monthly income (B=-5.531, p < 0.001), and education level (B = 3.956, p = 0.037) were influencing factors of physical QOL. Social frailty [1.6218, 95%CI (1.3006, 1.9444)] mediates between physical frailty and physical QOL. In addition, physical frailty [0.2289, 95%CI (0.0403, 0.4285)] mediates between social frailty and emotional QOL.
conclusionsAge, monthly income, and marital status influenced the level of emotional QOL in older heart failure inpatients; NYHA classes, monthly income, and education level are influencing factors of physical QOL. Social frailty mediates between physical frailty and physical QOL; physical frailty mediates between social frailty and emotional QOL.
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