ArticleBMC infectious diseases2025
Construction and verification of a new staging system for Osteoarticular tuberculosis-retrospective study.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo establish a unified tuberculosis staging system for trunk and limbs joints (Osteoarticular tuberculosis At Qinghai Fourth People's Hospital, QFOT), and verify the rationality and applicability of the classification system.
methodSearching our hospital's electronic medical record database from 2019 to 2022, including data of patients with bone and joint tuberculosis according to preset inclusion and exclusion criteria, and formulating a bone and joint tuberculosis staging system of the Fourth People's Hospital of Qinghai Province based on imaging data related to bone collapse, abscess flow metastasis, mechanical axis deviations, stable bone structure, joint deformity and other characteristics. Then, gender distribution, age distribution, whether surgery, pre-operation anti-tuberculosis drug treatment courses, white blood cell count, RBC sedimentation rate, C-reactive protein and serum procalcitonin were analyzed statistically. Understand the characteristics of Osteoarticular tuberculosis cases in different stages and verify the rationality of the QFOT staging system.
resultsA total of 16,487 tuberculosis patients were admitted to our hospital from 2019 to 2022, and a total of 509 patients with Osteoarticular tuberculosis were finally included, aged 41.1 ± 16.39 years. According to the QFOT staging system, 202 patients with stage I tuberculosis, 164 patients with stage II tuberculosis, 107 patients with stage III tuberculosis, 29 patients with stage IV tuberculosis, and 1 patient with stage V tuberculosis were classified. There were no significant differences in gender and age distribution of patients in different stages. There is a significant difference in the distribution of whether or not anti-tuberculosis drugs were used before surgery. There was no significant difference in white blood cell count levels among patients with different stages of Osteoarticular tuberculosis, and there were significant differences in red blood cell sedimentation rate and C-reactive protein levels. There are significant differences in the distribution of serum procalcitonin in patients with different stages of Osteoarticular tuberculosis.
conclusionThe QFOT staging system stages according to the pathological process of bone and joint tuberculosis. The verification results found that the QFOT staging system is scientific, but due to the small number of stage V patients included, further research is still needed to verify and improve this typing method. CLINICAL TRIAL NUMBER: Not applicable.
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