Evidence map›Paper›PMID 41249975›Full record

ArticleBMC public health2025

Validation of cognitive and psychosocial tools in Kenya: findings from the LOSHAK feasibility pilot.

Sneha Sarah Mani, Roselyter Monchari Riang'a, Niranjani Nagarajan, Anthony K Ngugi, Eunice Muthoni Mwangi, Muthoni Gichu, Patrick N Mwangala, Edward Miguel, Michael Walker, Kenneth M Langa and 2 more

Abstract readValidation Study
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Sneha Sarah ManiDepartment of Epidemiology, School of Public Health, Johns Hopkins University, Baltimore, USA. smani9@jh.edu.
Roselyter Monchari Riang'aDepartment of Population Health, Medical College, Aga Khan University, Nairobi, Kenya.
Niranjani NagarajanDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, USA.
Anthony K NgugiDepartment of Population Health, Medical College, Aga Khan University, Nairobi, Kenya.
Eunice Muthoni MwangiDepartment of Population Health, Medical College, Aga Khan University, Nairobi, Kenya.
Muthoni GichuDivision of Palliative and Aged Care, Ministry of Health, Nairobi, Kenya.
Patrick N MwangalaInstitute for Human Development, Aga Khan University, Nairobi, Kenya.
Edward MiguelUniversity of California - Berkeley, Berkeley, USA.
Michael WalkerUniversity of California - Berkeley, Berkeley, USA.
Kenneth M LangaSurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, USA.
Joshua R EhrlichDepartment of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, USA.
Alden L GrossDepartment of Epidemiology, School of Public Health, Johns Hopkins University, Baltimore, USA.

Funding

Statistical Data EnclaveP30AG012846 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI VICKI A. FREEDMAN · 1999 to 2026
$23.2M
The Longitudinal Study of Health and Ageing in Kenya (LOSHAK): A Population study of Health, Wellbeing, Economics, and AD/ADRD in Older Kenyan AdultsR01AG093721 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Joshua Robert Ehrlich, Anthony Karanja Ngugi · 2025 to 2026
$7.7M
Research Network for the Harmonized Cognitive Assessment Protocol (HCAP): Years 6-10U24AG065182 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lindsay C Kobayashi, KENNETH M LANGA · 2022 to 2026
$2.6M
Longitudinal Study of Health and Ageing in Kenya (LOSHAK)R21AG077042 · NIA · AGA KHAN UNIVERSITY (KENYA) · PI EHRLICH, JOSHUA ROBERT, NGUGI, ANTHONY KARANJA · 2022 to 2022
$339k
Michigan Center on the Demography of Aging's HRS Partner Studies Network P30AG012846NIA NIH HHS P30 AG012846NIA NIH HHS R01 AG093721NIA NIH HHS R21 AG077042NIA NIH HHS R21AG077042NIA NIH HHS U24 AG065182University of Michigan Center for Global Health Equity; Harmonized Cognitive Assessment Protocol Network U24AG065182
6 · The paper itself

Abstract

BACKGROUND AND

objectivesAdapting cognitive tests to culturally diverse and low-resource settings is essential for expanding knowledge of cognitive health in older adults beyond high-income countries. However, contextual differences in novel settings can affect reliability and validity. There is limited evidence on the feasibility of implementing culturally adapted cognitive assessments in Sub-Saharan Africa, a region projected to have over 158 million adults aged 60 and older by 2050. The Longitudinal Study of Health and Ageing in Kenya (LOSHAK) is designed to address this measurement gap by evaluating cognitive tests in this context. RESEARCH DESIGN AND

methodsWe analyzed data from 205 adults aged 45 years and older from the Kaloleni/Rabai Health and Demographic Surveillance System in Coastal Kenya. Using McDonald's omega and confirmatory factor analysis, we evaluated the internal consistency reliability and the factor structure of four cognitive domains (orientation, memory, executive functioning, language/fluency) and four psychosocial constructs (depressive symptoms, loneliness, subjective well-being, and life satisfaction).

resultsMcDonald's omegas ranged from ω = 0.78 to 0.95 for cognitive domains and were above 0.83 for each psychosocial domain, suggesting high reliability. Factor analyses revealed adequate to perfect fit for most domains, and patterns of factor loadings were mostly acceptable.

conclusionThe successful adaptation of these assessment tools in Kenya demonstrates the feasibility of implementing rigorous cognitive and psychosocial measurements in low-resource settings. These findings provide a methodological framework for future aging studies in similar contexts across Sub-Saharan Africa.

Indexed as

CognitionNeuropsychological TestsAgedAged, 80 and overFactor Analysis, StatisticalFeasibility StudiesFemaleHumansKenyaLongitudinal StudiesMaleMiddle AgedPilot ProjectsPsychometricsReproducibility of ResultsCognitionDementiaSub-Saharan AfricaSuccessful agingValidation

Identifiers

PMID41249975
PMCPMC12625501

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.