Evidence map›Paper›PMID 41249962›Full record

ArticleBMC medical imaging2025

Diffusion-T2 correlated spectroscopy imaging to explore possible placental composition changes over gestation.

Xilong Liu, Chantao Huang, Sijin Chen, Jie Feng, Wenjun Qiao, Bo Liu, Wentao Hu, Yongming Dai, Yikai Xu

Abstract read
In one paragraph

Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xilong Liu *Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, Guangdong, 510515, China. xilongl@sina.com.
Chantao Huang *Department of Medical Imaging Center, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, Guangdong, 510515, China.
Sijin Chen *Department of Obstetrics and Gynecology, Nanfang Hospital Taihe Branch, Southern Medical University, Guangzhou, China.
Jie FengDepartment of Medical Imaging Center, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, Guangdong, 510515, China.
Wenjun QiaoDepartment of Medical Imaging Center, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, Guangdong, 510515, China.
Bo LiuDepartment of Medical Imaging Center, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, Guangdong, 510515, China.
Wentao HuDepartment of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yongming DaiSchool of Biomedical Engineering, ShanghaiTech University, Shanghai, China.
Yikai XuDepartment of Medical Imaging Center, Nanfang Hospital, Southern Medical University, 1838 Guangzhou North Road, Guangzhou, Guangdong, 510515, China. yikai.xu@163.com.

Funding

Guangzhou Health Science and Technology Project 20241A011109Medical Scientific Research Foundation of Guangdong Province A2023172Medical Scientific Research Foundation of Guangdong Province B2025721
6 · The paper itself

Abstract

backgroundPlacenta plays a vital role for fetal growth and development during pregnancy. Currently, antenatal noninvasive imaging techniques to directly evaluate placental function remains challenge. Diffusion-T2 correlated spectroscopy imaging (DT2SI) can provide compositional information for different organs in-vivo. The aim of this study was to investigate the use of DT2SI as a tool to elucidate the placental composition change over gestation in healthy pregnancy.

methodsForty healthy singleton pregnancies were retrieved from our placental MRI research database. MRI was performed at 23.1-36.0 weeks of gestational age (GA) in a 3.0T system. DT2SI measurements were performed using DWI sequence with 7 b-values combining 4 TEs. ROIs were manually defined inside placenta on five cross-sectional slices covering the most central part of placenta. D-T2 Spectra were constructed and segmented into 9 compartments: A1

resultsFour to five peaks could be observed in the spectrum for most subjects. Strong correlation between DT2SI V

conclusionsComprehensive information on evolution of placenta composition with gestation could be provided by DT2SI, suggesting its unique value for assessing placental function during pregnancy.

Indexed as

Diffusion Magnetic Resonance ImagingPlacentaAdultFemaleGestational AgeHumansPregnancyYoung AdultDiffusionMaternal-fetal medicineMRIPlacentaPregnancyT2 relaxometry

Identifiers

PMID41249962
PMCPMC12625514

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.