ArticleBMC medical imaging2025
Diffusion-T2 correlated spectroscopy imaging to explore possible placental composition changes over gestation.
Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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9 authors.
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Abstract
backgroundPlacenta plays a vital role for fetal growth and development during pregnancy. Currently, antenatal noninvasive imaging techniques to directly evaluate placental function remains challenge. Diffusion-T2 correlated spectroscopy imaging (DT2SI) can provide compositional information for different organs in-vivo. The aim of this study was to investigate the use of DT2SI as a tool to elucidate the placental composition change over gestation in healthy pregnancy.
methodsForty healthy singleton pregnancies were retrieved from our placental MRI research database. MRI was performed at 23.1-36.0 weeks of gestational age (GA) in a 3.0T system. DT2SI measurements were performed using DWI sequence with 7 b-values combining 4 TEs. ROIs were manually defined inside placenta on five cross-sectional slices covering the most central part of placenta. D-T2 Spectra were constructed and segmented into 9 compartments: A1
resultsFour to five peaks could be observed in the spectrum for most subjects. Strong correlation between DT2SI V
conclusionsComprehensive information on evolution of placenta composition with gestation could be provided by DT2SI, suggesting its unique value for assessing placental function during pregnancy.
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