Evidence map›Paper›PMID 41249935›Full record

ArticleBMC plant biology2025

The role of ACS genes in sex differentiation of Siraitia grosvenorii revealed by comparative transcriptomic analysis.

Changming Mo, Fang Qin, Wenfeng Guo, Qi Tang, Zhong Li, Limei Pan, Zuliang Luo, Chongnan Wang, Renfan Liang

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Changming MoGuangxi Academy of Agricultural Sciences, Nanning, 530007, China.
Fang QinGuangxi Botanical Garden of Medicinal Plants, Nanning, 530023, China.
Wenfeng GuoGuangxi Academy of Agricultural Sciences, Nanning, 530007, China.
Qi TangCollege of Horticulture, Hunan Agricultural University, Changsha, 410128, China.
Zhong LiGuangxi Academy of Agricultural Sciences, Nanning, 530007, China.
Limei PanGuangxi Botanical Garden of Medicinal Plants, Nanning, 530023, China.
Zuliang LuoState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Medicinal Plant Development Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100193, P.R. China.
Chongnan WangState Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, Institute of Medicinal Plant Development Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100193, P.R. China.
Renfan LiangGuangxi Academy of Agricultural Sciences, Nanning, 530007, China. gxnkylrf@gxaas.net.

Funding

Key Project of Hunan Provincial Science & Technology Department No. 2022NK2004National Key Research and Development Program of China No. 2023YFD1200200National Natural Science Foundation of China No. U20A2004
6 · The paper itself

Abstract

backgroundSiraitia grosvenorii, commonly known as monk fruit, was one of the first approved medicinal food homologs. However, few studies have focused the network of interactions between genetic factors and hormones involved in flowering regulation and sex differentiation in this important member. This study aimed to explore the mechanisms by which sexual differentiation in S. grosvenorii is regulated; thus, we analyzed differentially expressed genes (DEGs), pathways, and aminocyclopropane-1-carboxylate synthase (ACS)-related gene expression.

resultsAnalysis of ethephon-induced morphological changes showed that ethylene promoted senescence and death of the female stem terminals of S. grosvenorii plants when significantly higher ACS expression occurred in female plants. Additionally, a larger number of DEGs characterized the male than the female reproductive stage, including 4,044 up-regulated and 3,798 down-regulated genes. These DEGs were significantly enriched in phenylalanine metabolism, phenylpropanoid biosynthesis, and plant hormone-signal transduction. Moreover, ethylene synthesis and signal transduction pathways included 43 differentially expressed transcripts (ACS and 1-aminocyclopropane-1-carboxylate oxidase), whereas the cytokinin synthesis and signal transduction pathways included 34 differentially expressed transcripts. Lastly, overexpression of either SgACS1G or SgACS7 in Arabidopsis thaliana suppressed stamen development.

conclusionsOur study provides a solid theoretical basis for the unequivocal identification of male and female plants and flowering regulation in S. grosvenorii plants to guide breeding strategies.

Indexed as

CucurbitaceaeLyasesPlant ProteinsEthylenesFlowersGene Expression ProfilingGene Expression Regulation, PlantGenes, PlantPlant Growth RegulatorsSignal TransductionTranscriptome1-aminocyclopropanecarboxylate synthaseethyleneEthylenesLyasesPlant Growth RegulatorsPlant Proteins1-aminocyclopropane-1-carboxylate synthaseEthyleneFemale flowerSexual reproductionSiraitia grosvenorii

Identifiers

PMID41249935
PMCPMC12625138

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