Evidence map›Paper›PMID 41249773›Full record

ArticleMicrobial biotechnology2025

Metabolic Origin, Role and Fate of the Denaturant Guanidine.

Antoine Danchin, Victor de Lorenzo, Pablo Iván Nikel, Conghui You

Abstract read
In one paragraph

Article in Microbial biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Antoine DanchinSchool of Biomedical Sciences, Li KaShing Faculty of Medicine, Hong Kong University, Pokfulam, SAR Hong Kong, China.ORCID 0000-0002-6350-5001
Victor de LorenzoSystems Biology Department, Centro Nacional de Biotecnologia, CSIC, Madrid, Spain.ORCID 0000-0002-6041-2731
Pablo Iván NikelThe Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kongens Lyngby, Denmark.ORCID 0000-0002-9313-7481
Conghui YouDepartment of Pathogenic Biology and Immunology, Jiangsu Provincial Key Laboratory of Critical Care Medicine, School of Medicine, Southeast University, Nanjing, Jiangsu, China.

Funding

European Union's Horizon 2020 Research and Innovation Programme 101082049 (TOLERATE)European Union's Horizon 2020 Research and Innovation Programme 814418 (SinFonia)Start-up Research Fund of Southeast University RF1028624167The Novo Nordisk Foundation LiFe (NNF18OC0034818)The Novo Nordisk Foundation NNF20CC0035580The Novo Nordisk Foundation TARGET (NNF21OC0067996)
6 · The paper itself

Abstract

Despite its unusual structure and detrimental role as a chaotropic guanidinium ion, guanidine [HNC(NH

Indexed as

BacteriaGuanidineMetabolic Networks and PathwaysOxidation-ReductionOxygenPurinesGuanidineOxygenPurinesdehydro‐guanidinohydantoindioxygenasenickelriboswitchsmall multidrug resistance transportertranslation elongation factor EF‐Purea

Identifiers

PMID41249773
PMCPMC12623156

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.