SynthesisJournal of perinatology : official journal of the California Perinatal Association2026
MRI scoring systems in neonatal encephalopathy and neurodevelopmental outcomes: a systematic review.
Synthesis in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Establishment of a Simplified Clinical Scoring System for Neurodevelopmental Follow-Up and Its Application in Very Preterm Infants.Child: care, health and development · 2026Article
- Magnetic Resonance Imaging of the Neonatal Brain: Modalities, Scoring Systems, and Clinical Applications.Bioengineering (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neonatal brain MRI is standard of care for neuroimaging in infants with neonatal encephalopathy (NE); no international consensus exists on scoring systems to predict neurodevelopmental outcomes. This systematic review evaluates the predictive performance of existing neonatal MRI scoring systems for NE. Cochrane and PRISMA guidelines were adhered to and the study was registered with PROSPERO. Key outcomes included MRI scoring correlation in infants born at ≥36 weeks with neurodevelopmental outcomes. Of 1525 studies retrieved, and 16 met the inclusion criteria, totalling 1925 participants with follow-up data. Scoring systems evaluated included NICHD, Rutherford, Weeke, Trivedi, Barkovich, and one newly developed score. Fifteen studies found an association with outcomes; one found no correlation with IQ or typical development. All MRI scoring systems have similar predictive accuracy. Simpler systems, such as NICHD, performed on par with more complex counterparts, suggesting they may offer a more efficient option in clinical settings.
Indexed as
Identifiers
41249593What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.