ArticleJournal of perinatology : official journal of the California Perinatal Association2026
Nasal intermittent positive pressure ventilation in neonates with grade 3 bronchopulmonary dysplasia.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveWe describe a novel strategy of nasal intermittent positive pressure ventilation (NIPPV) to support patients with Grade 3 bronchopulmonary dysplasia (BPD). STUDY
designThis is a retrospective study of Grade 3 BPD patients treated with NIPPV and discharged from a single center from January 2020 to May 2024. Patients were grouped into discharged without tracheostomy vs with tracheostomy. Groups were assessed for clinical differences, and the NIPPV strategy is described.
resultsThere were 28 non-tracheostomy and 17 tracheostomy patients. There were no differences in gestational age, birthweight, or respiratory severity score at key dates. Tracheostomy patients were more likely to have subglottic stenosis (53% vs 3.6%, p = 0.0001) and were older at discharge home [median 447 (411-479) vs 252 (184-309) days, p < 0.0001].
conclusionA subset of Grade 3 BPD patients can be supported with NIPPV. The non-tracheostomy group had decreased length of stay compared to the tracheostomy group.
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