Evidence map›Paper›PMID 41249536›Full record

Observational studySurgical endoscopy2026

Learning curve for direct nasofibrolaryngoscopy in an endocrine surgery unit.

Norberto Cassinello Fernández, Marina Riera Cardona, Adrian Jareño Silvestre, Raquel Alfonso Ballester, Rosa Maria Martí Fernández, Maria Lapeña Rodríguez

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Norberto Cassinello FernándezEndocrine Surgery Department, Hospital Clínico Universitario, Valencia, Spain. cassinello73@hotmail.com.ORCID 0000-0002-9741-1134
Marina Riera CardonaEndocrine Surgery Department, Hospital Clínico Universitario, Valencia, Spain.
Adrian Jareño SilvestreEndocrine Surgery Department, Hospital Clínico Universitario, Valencia, Spain.
Raquel Alfonso BallesterEndocrine Surgery Department, Hospital Clínico Universitario, Valencia, Spain.
Rosa Maria Martí FernándezEndocrine Surgery Department, Hospital Clínico Universitario, Valencia, Spain.
Maria Lapeña RodríguezEndocrine Surgery Department, Hospital Clínico Universitario, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInjury to the recurrent laryngeal nerve (RLN) is a specific complication of thyroid surgery. Flexible direct nasofibrolaryngoscopy (DNFL) is the gold standard for evaluating vocal cord mobility, although its systematic use and learning curve among endocrine surgeons remain poorly defined. The aim of this study is to identify factors related to the final result and how explorer experience or patient characteristics could influence in the evolution of the learning curve.

methodsRetrospective observational study included 110 consecutive patients who underwent thyroid surgery between June 2022 and February 2024. A total of 123 DNFL procedures were performed by junior and senior endocrine surgeons, all of them without prior experience in the technique. Variables analyzed included demographic and clinical data, exploration time, and procedural success. Comparative statistical analysis, multivariate linear regression, and cumulative sum (CUSUM) analysis were used to evaluate the learning curve.

resultsDFNL was successfully completed in 93.5% of cases, with no complications reported. The mean exploration time was 75.28 ± 58.23 s. Significant differences were observed in relation to study period (p < 0.01) and surgeon experience (p < 0.01); but not with pathology or patient characteristics. The regression model confirmed a gradual reduction in exploration time with increased experience. CUSUM analysis identified three learning phases and showed that performance stabilized after 35-40 procedures, regardless of the surgeon's level of experience.

conclusionDNFL was safe with a short and well-defined learning curve. Its integration into endocrine surgery practice may be feasible even for surgeons without prior experience.

Indexed as

LaryngoscopyLearning CurveRecurrent Laryngeal Nerve InjuriesThyroidectomyAdultAgedClinical CompetenceFemaleHumansMaleMiddle AgedRetrospective StudiesDirect nasofibrolaryngoscopyEndocrine surgeryLearning curve

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.