Evidence map›Paper›PMID 41249529›Full record

ArticleAesthetic plastic surgery2026

Orbital Septum-Periocular Tissue Connections and Septal Histological Characteristics in Mild Ptosis During Blepharoplasty.

Huiming She, Xin Chen, Gaofeng Li, Ting Yang, Qian Chen, Youqi Luo, Wanhong Zhang

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Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Huiming She *Department of Plastic and Laser Cosmetology, The First Affiliated Hospital of Hunan Normal University, Hunan Provincial People's Hospital, Changsha, Hunan, People's Republic of China.
Xin Chen *Department of Plastic and Laser Cosmetology, The First Affiliated Hospital of Hunan Normal University, Hunan Provincial People's Hospital, Changsha, Hunan, People's Republic of China.
Gaofeng LiDepartment of Plastic and Laser Cosmetology, The First Affiliated Hospital of Hunan Normal University, Hunan Provincial People's Hospital, Changsha, Hunan, People's Republic of China. ligf01@126.com.ORCID 0000-0002-0033-7389
Ting YangPathology Department, The First Affiliated Hospital of Hunan Normal University, Hunan Provincial People's Hospital, Changsha, Hunan, People's Republic of China.
Qian ChenDepartment of Plastic and Laser Cosmetology, The First Affiliated Hospital of Hunan Normal University, Hunan Provincial People's Hospital, Changsha, Hunan, People's Republic of China.
Youqi LuoDepartment of Plastic and Laser Cosmetology, The First Affiliated Hospital of Hunan Normal University, Hunan Provincial People's Hospital, Changsha, Hunan, People's Republic of China.
Wanhong ZhangDepartment of Plastic and Laser Cosmetology, The First Affiliated Hospital of Hunan Normal University, Hunan Provincial People's Hospital, Changsha, Hunan, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the anatomical connections and histological features of the orbital septum in patients with mild ptosis undergoing blepharoplasty.

methodsFrom May 2018 to December 2019, we studied 276 blepharoplasty patients (549 eyes) divided into normal (498 eyes) and mild ptosis (51 eyes) groups. The study focused on the orbital septum, examining its adjacent structures and histological composition.

resultsAmong 498 normal eyes and 51 eyes with mild ptosis, the mild ptosis group exhibited a significantly increased incidence of orbital septum to orbital fat envelope adhesions (χ2 = 95.00, P < 0.001) and of transverse ligament formation between the orbital septum and the upper levator aponeurosis (χ2 = 99.00, P < 0.001) compared to the normal group. Hematoxylin-eosin staining (HE staining) demonstrated that the orbital septum in both groups predominantly consists of a bilayered connective tissue, with a looser anterior layer and a denser posterior layer. In the mild ptosis group, the connective tissue fibers were found to be sparser and more relaxed compared to the normal group. Masson and immunohistochemical staining (α-SMA) revealed the absence of muscular elements within the orbital septum in both groups.

conclusionAdhesions between the orbital septum and the orbital fat envelope and transverse ligament between the orbital septum and the levator aponeurosis may be the cause of mild ptosis. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

BlepharoplastyBlepharoptosisOrbitAdipose TissueAdultAgedFemaleHumansMaleMiddle AgedOculomotor MusclesRetrospective StudiesSeverity of Illness IndexTissue AdhesionsYoung AdultLevator aponeurosisMild ptosisOrbital septumUpper BlepharoplastyUpper eyelid

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.