Evidence map›Paper›PMID 41249159›Full record

ArticleScientific data2025

A relaxation-diffusion MRI dataset of aging mouse brains at 9.4 Tesla.

Baoxing Ren, Ye Wu, Yan Liu, Yongpeng Bai, Quan Tao, Yanqiu Feng, Xinyuan Zhang

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Baoxing RenSchool of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China.
Ye WuSchool of Computer Science and Technology, Nanjing University of Science and Technology, Nanjing, 210094, China.
Yan LiuSchool of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China.
Yongpeng BaiSchool of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China.
Quan TaoSchool of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China.
Yanqiu FengSchool of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China. foree@163.com.
Xinyuan ZhangSchool of Biomedical Engineering, Southern Medical University, Guangzhou, 510515, China. zhangxyn@smu.edu.cn.ORCID 0000-0002-1737-6069

Funding

National Natural Science Foundation of China (National Science Foundation of China) 62201265National Natural Science Foundation of China (National Science Foundation of China) 82372079National Natural Science Foundation of China (National Science Foundation of China) U21A6005
6 · The paper itself

Abstract

Relaxation-diffusion MRI (rdMRI) is an advanced imaging technique that acquires diffusion MRI data across multiple echo times (TEs), enabling the disentanglement of relaxation and diffusion effects. This approach offers deeper insights into tissue microstructure, making it especially powerful for studying complex tissue organization and developmental processes. However, the lack of publicly available rdMRI datasets in mouse models has significantly limited its application in preclinical research. Here, we present a high-quality in-vivo rdMRI dataset of aging mouse brains, collected from five different age groups (n = 6 per group) using a 9.4 T ultra-high field MRI scanner. The rdMRI data were acquired at 5 different TEs, with multi-shell diffusion scans at each TE. Each rdMRI dataset was processed through a specialized pipeline, with systematic quality control to ensure the reliability of the data. This dataset provides a foundation for validating and optimizing rdMRI techniques and serves as a valuable resource for investigating age-related structural alterations in the mouse brain.

Indexed as

AgingBrainDiffusion Magnetic Resonance ImagingAnimalsMice

Identifiers

PMID41249159
PMCPMC12624103

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.