ArticleThe British journal of ophthalmology2026
Adult myopia progression in high myopes aged 18-25 years: evidence from a population-based cohort.
Article in The British journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Prediction of axial elongation in adults with high myopia: the Wenzhou High Myopia Cohort Study.Eye and vision (London, England) · 2026Article
- Intraocular Pressure-Lowering Therapy Slows Down Axial Elongation in Progressive High Myopia with Enhanced Choroidal Perfusion.Ophthalmology science · 2026Article
- Association between first-year axial elongation and 10-year myopia progression in children wearing orthokeratology lenses: a ten-year longitudinal study.Frontiers in cell and developmental biology · 2026Article
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Authors and funding
12 authors.
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No grant is acknowledged in the PubMed record.
Abstract
aimsTo investigate the prevalence and severity of adult myopia progression among highly myopic individuals aged 18-25 years, identify its associated factors and evaluate its association with pathologic myopia (PM).
methodsWe retrospectively included participants aged 18-25 years with consecutive follow-ups from the Shanghai Child and Adolescent Large-scale Eye Study database. Annual changes of cycloplegic spherical equivalent (ΔSE) and axial length (ΔAL) were calculated. Adult myopia progression is defined as ΔSE ≤-0.50 D/year or ΔAL≥0.10 mm/year. PM was diagnosed based on META-Analysis for Pathologic Myopia criteria (category≥2) and optical coherence tomography (OCT) images.
resultsAmong all included 345 eyes, the mean ΔSE was -0.28 D/year (95% CI -0.31 to -0.20; p<0.001) and 64 (18.6%) were classified as having adult myopia progression. The mean ΔAL was 0.09 mm/year (95% CI 0.09 to 0.10; p<0.001), with axial elongation observed in 138 (40.0%) eyes. Both age (ΔSE: β=0.045, p=0.005; ΔAL: β=-0.015, p<0.001) and baseline AL (ΔSE: β=-0.044, p=0.028; ΔAL: β=0.020, p<0.001) were identified as factors associated with ΔSE and ΔAL. No differences in ΔSE (95% CI -0.08 to 0.11; p=0.759) or ΔAL (95% CI -0.04 to 0.01; p=0.190) were found between PM and non-PM groups, and neither metric improved PM discrimination.
conclusionsAmong high myopic individuals aged 18-25 years, 18.6% exhibited adult myopia progression and 40.0% showed axial elongation. Age and baseline AL were associated with adult myopia progression, but no clear link was found between adult myopia progression and the development of PM.
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