Evidence map›Paper›PMID 41248434›Full record

ArticleJournal of proteome research2025

MetScribeR: A Semiautomated Tool for Data Processing of In-House LC-MS Metabolite Reference Libraries.

Adam M Tisch, Jason M Inman, Ewy A Mathé, Djawed Bennouna

Abstract read
In one paragraph

Article in Journal of proteome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Adam M TischDivision of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), Rockville, Maryland 20850, United States.
Jason M InmanDivision of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), Rockville, Maryland 20850, United States.
Ewy A MathéDivision of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), Rockville, Maryland 20850, United States.ORCID 0000-0003-4491-8107
Djawed BennounaDivision of Preclinical Innovation, National Center for Advancing Translational Sciences (NCATS), Rockville, Maryland 20850, United States.ORCID 0000-0002-4194-4046

Funding

Informatics Research CoreZICTR000410 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI MATHÉ, EWY · 2021 to 2025
$11.7M
Intramural NIH HHS ZIC TR000410
6 · The paper itself

Abstract

One persistent challenge in untargeted metabolomics is the identification of compounds from their mass spectrometry (MS) signal, which is necessary for biological data interpretation. This process can be facilitated by building in-house libraries of metabolite standards containing retention time (RT) information, which is orthogonal and complementary to large, published MS/MS spectra repositories. Creating such libraries can require substantial effort and is time intensive. To streamline this process, we developed metScribeR, an R package with a Shiny application to accelerate the creation of RT and

Indexed as

MetabolomicsSoftwareTandem Mass SpectrometryChromatography, LiquidLiquid Chromatography-Mass SpectrometryReference StandardsLC-MSmass spectrometrymetabolite identificationmetabolite librariesmetabolomicsRsoftware

Identifiers

PMID41248434
PMCPMC12687357

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.