Evidence map›Paper›PMID 41248406›Full record

ArticleBMJ open2025

Qualitative evaluation of the barriers and facilitators to a retrospective hepatitis C virus patient re-engagement exercise in England .

Avelie Stuart, Carina Hörst, David Etoori, Fabiana Lorencatto, William Rosenberg, Catherine Lowndes, Ruth Simmons, Sema Mandal, Mark Gillyon-Powell, Monica Desai

Abstract read
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Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Avelie StuartUK Health Security Agency, London, UK.ORCID http://orcid.org/0000-0001-7711-6149
Carina HörstUK Health Security Agency, London, UK.
David EtooriCentre for Clinical Research, Epidemiology, Modelling and Evaluation (CREME), Institute for Global Health, University College London, London, UK.ORCID http://orcid.org/0000-0002-2807-6272
Fabiana LorencattoNIHR Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections, London, UK f.lorencatto@ucl.ac.uk.
William RosenbergNIHR Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections, London, UK.
Catherine LowndesUK Health Security Agency, London, UK.
Ruth SimmonsUK Health Security Agency, London, UK.
Sema MandalUK Health Security Agency, London, UK.
Mark Gillyon-PowellSpecialised Commissioning, NHS England, London, UK.
Monica DesaiUK Health Security Agency, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe UK Health Security Agency and the National Health Service England (NHSE) led a hepatitis C virus (HCV) patient re-engagement exercise beginning in 2018, which entailed sharing public health surveillance data with NHSE Operational Delivery Networks (ODNs) in England. The ODNs used the data to contact and offer testing and treatment to people historically diagnosed with HCV, but who did not have evidence of successfully clearing the virus. A quantitative evaluation found that of 55 329 individuals whose details were shared with ODNs, around 13% had treatment after the exercise commenced. This qualitative evaluation aims to identify the barriers and facilitators to the re-engagement exercise as reported by ODN staff.

designSemistructured interviews. The topic guide and analysis were guided by the Theoretical Domains Framework, using a combined deductive framework and inductive thematic analysis approach. SETTING AND

participants21 staff from 13 ODNs. The sampling frame was designed to capture participants from all regions of England and with varied outcomes from the re-engagement exercise.

resultsInterviewees reported the most barriers in environmental context and resources (including staffing limitations, interruptions during COVID-19, restricted laboratory access), and social influences (with limited responses from general practitioners and patients). Interviewees discussed whether it was appropriate for ODNs and individual staff to be assigned the data validation work and reported some stress and memory/attention barriers due to the volume of the exercise. They had varied beliefs about the consequences of the exercise, with most believing it was worthwhile due to treatment yield, lessons learnt and confirmation that some people had cleared the virus. Further facilitators included the ODN goals fitting with the exercise, and regional resources such as patient databases. Interviewees also reported adaptations to the exercise that facilitated patient contact, and their ongoing work to re-engage patients emphasised outreach partnerships and peer support.

conclusionsThe evaluation revealed insights into methods for re-engaging patients and of sharing and using public health data to support clinical practice. Government support and funding provision for regionally tailored holistic re-engagement approaches, alongside enhancements to health surveillance data, could enable barriers to re-engagement to be overcome.

Indexed as

Hepatitis CPatient ParticipationCOVID-19EnglandFemaleHumansInterviews as TopicMaleQualitative ResearchRetrospective StudiesSARS-CoV-2State MedicineHepatologyPatient Care ManagementPublic healthQUALITATIVE RESEARCH

Identifiers

PMID41248406
PMCPMC12625882

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.