Evidence map›Paper›PMID 41248399›Full record

ArticleBMJ open2025

Efficacy of transcutaneous electrical acupoint stimulation for the treatment of gastrointestinal dysfunction in patients after cardiac surgery with cardiopulmonary bypass: study protocol for a superiority, single-centre, single-blind, randomised controlled clinical trial.

Yingying Liao, Qiong Gao, Yanxian Chen, Hui Li, Jing Wang, Fengnan Zheng, Shaoyan Lin

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yingying LiaoDepartment of Cardiovascular Surgery, Southern Medical University Nanfang Hospital, Guangzhou, China.ORCID http://orcid.org/0009-0002-5413-973X
Qiong GaoDepartment of Cardiovascular Surgery, Southern Medical University Nanfang Hospital, Guangzhou, China.
Yanxian ChenDepartment of Cardiovascular Surgery, Southern Medical University Nanfang Hospital, Guangzhou, China.
Hui LiDepartment of Cardiovascular Surgery, Southern Medical University Nanfang Hospital, Guangzhou, China.
Jing WangDepartment of Cardiovascular Surgery, Southern Medical University Nanfang Hospital, Guangzhou, China.
Fengnan ZhengDepartment of Cardiovascular Surgery, Southern Medical University Nanfang Hospital, Guangzhou, China.
Shaoyan LinDepartment of Cardiovascular Surgery, Southern Medical University Nanfang Hospital, Guangzhou, China 23684420@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGastrointestinal dysfunction is one of the most frequent complications in patients after cardiac surgery with cardiopulmonary bypass (CPB). It can seriously affect the patient's quality of life, increase the length of hospitalisation and in severe cases trigger cardiac arrest. This single-centre randomised controlled study aims to investigate whether transcutaneous electrical acupoint stimulation (TEAS) can effectively relieve gastrointestinal discomfort and improve the quality of life of patients after cardiac surgery. METHODS AND ANALYSIS: A total of 426 patients after cardiac surgery with CPB will be randomly assigned to the control group or intervention group (1:1 ratio) to receive either acupressure or TEAS for 3 days. The patients will be recruited from the Department of Cardiovascular Surgery of Nanfang Hospital. The primary outcome is the time of the first postoperative anal defecation, the secondary outcomes include the first postoperative anal exsufflation time, the number of bowel sounds, the proportion of postoperative laxatives used in the two groups, abdominal girth, stool frequency per day and length of postoperative hospital stay. ETHICS AND DISSEMINATION: The procedures have been approved by the Guangdong Regional Medical Ethics Committee of Nanfang Hospital (NFEC-2023-404) and conformed to the Declaration of Helsinki. Written informed consent will be obtained from all the participants. Results will be disseminated through workshops, peer-reviewed publications and conferences.

trial registrationRegistered in Chinese Trial Registry (https://www.chictr.org.cn/) on 1 November 2023 (Registered number: ChiCTR2300077211). Pre-result.

Indexed as

Acupuncture PointsCardiac Surgical ProceduresCardiopulmonary BypassGastrointestinal DiseasesPostoperative ComplicationsTranscutaneous Electric Nerve StimulationAdultDefecationEquivalence Trials as TopicFemaleHumansMaleMiddle AgedQuality of LifeRandomized Controlled Trials as TopicSingle-Blind MethodCardiac surgeryCOMPLEMENTARY MEDICINERandomized Controlled Trial

Identifiers

PMID41248399
PMCPMC12587976

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.