Evidence map›Paper›PMID 41248382›Full record

ArticleBMJ open2025

Evaluating economic outcomes in the management of temporomandibular disorders: a protocol for a systematic review of randomised controlled trials.

Purnima Komarraju, Berlant AlSabbagh, Arto Ohinmaa, Susan Armijo-Olivo, Martin Morris, Jingjing Li, Paul W Major, Michael Goldberg, Ayushi Naik, Aya Abdelkarim and 1 more

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Purnima KomarrajuDepartment of Dentistry, Jewish General Hospital, Montreal, Canada, Canada.
Berlant AlSabbaghDepartment of Dentistry, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada.ORCID http://orcid.org/0009-0000-2344-0138
Arto OhinmaaSchool of Public Health, University of Alberta, Edmonton, Alberta, Canada.
Susan Armijo-OlivoFaculty of Business and Social Science, University of Applied Sciences, Osnabrück, Germany.
Martin MorrisSchulich Library of Physical Sciences, Life Sciences and Engineering, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-5659-2995
Jingjing LiSchulich Library of Physical Sciences, Life Sciences and Engineering, McGill University, Montreal, Quebec, Canada.
Paul W MajorSchool of Public Health, University of Alberta, Edmonton, Alberta, Canada.
Michael GoldbergFaculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.
Ayushi NaikFaculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal, Quebec, Canada.ORCID http://orcid.org/0009-0004-6497-8646
Aya AbdelkarimFaculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal, Quebec, Canada.
Ana Miriam VellyDepartment of Dentistry, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada ana.velly@mcgill.ca.ORCID http://orcid.org/0000-0003-3125-1884

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSystematic reviews (SRs) on the management of temporomandibular disorders (TMDs) have predominantly focused on evaluating the effectiveness of various treatments, identifying those that provide the greatest benefits. However, the economic evaluation of these treatments has not been systematically explored. This SR aims to address this gap by evaluating the economic outcomes of the most common treatment modalities for TMDs, including cost-effectiveness, cost-utility, cost-benefit, cost-minimisation and the burden of illness. METHODS AND ANALYSIS: This SR will be conducted using the following electronic databases Business Source Complete, CINAHL, EconLit (ProQuest), Embase (Ovid), MEDLINE (PubMed), MEDLINE (Ovid) and Scopus to identify studies evaluating the economic outcomes of treatments for TMDs. The eligibility criteria are as follows: (1) studies examining the costs and/or impact of treatments for TMDs and (2) articles published between 2000 and 2025. The primary outcomes of interest are the economic findings outlined earlier. Data extraction will include the following: author(s), year of publication, country, study objectives, study design, eligibility criteria, TMD diagnosis and screening, study groups, randomisation, blinding, sample size, number of participants invited, enrolled and completed, duration of treatment, follow-up, study duration, settings, assessment instruments, study outcomes, statistical analyses, results, limitations, strengths and funding sources. The quality of studies will be evaluated using the Consolidated Health Economic Evaluation Reporting Standards 2022 checklist, with risk of bias assessed using the Cochrane Effective Practice and Organization of Care's risk-of-bias tool; where applicable, the Outcome Reporting Bias in Trials will be used to detect reporting biases. A narrative synthesis and summary tables will outline study characteristics, economic outcomes and the overall quality of evidence. We will conduct qualitative secondary and sensitivity analyses. ETHICS AND DISSEMINATION: This SR does not require an ethics approval. The results will be disseminated through international and national conferences and peer-reviewed journals. PROSPERO REGISTRATION NUMBER: CRD42024613553.

Indexed as

Temporomandibular Joint DisordersCost-Benefit AnalysisCost of IllnessHumansRandomized Controlled Trials as TopicResearch DesignSystematic Reviews as TopicChronic PainHealth Care CostsHEALTH ECONOMICSPAIN MANAGEMENTSystematic Review

Identifiers

PMID41248382
PMCPMC12588002

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.