Evidence map›Paper›PMID 41248365›Full record

ArticleBMJ open2025

Enhancing healthcare providers' advance care planning competence with large language models: protocol for the development of an AI chatbot and its evaluation in a randomised controlled trial.

Minghui Tan, Siyuan Tang, Shichao Kan, Haojie Zhang, Bei Wu, Zhao Ni, Chia Chin Lin, Jinfeng Ding

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Minghui TanXiangya School of Nursing, Central South University, Changsha, Hunan, China.ORCID http://orcid.org/0000-0002-4341-1892
Siyuan TangSchool of Nursing, Ningxia Medical University, Yinchuan, China.
Shichao KanSchool of Computer Science and Engineering, Central South University, Changsha, China.
Haojie ZhangSchool of Computer Science and Engineering, Central South University, Changsha, China.
Bei WuRory Meyers College of Nursing, New York University, New York, New York, USA.ORCID http://orcid.org/0000-0002-6891-244X
Zhao NiSchool of Nursing, Yale University, New Haven, Connecticut, USA.
Chia Chin LinThe University of Hong Kong, Hong Kong, Hong Kong.
Jinfeng DingXiangya School of Nursing, Central South University, Changsha, Hunan, China jinfeng.ding@csu.edu.cn.ORCID http://orcid.org/0000-0002-8783-8919

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdvance care planning (ACP) can support individuals to express their autonomy in the decision-making process for future care. Traditional ACP training for healthcare providers faces significant challenges related to interactivity, accessibility, scalability and sustainability. Cutting-edge generative artificial intelligence (AI) holds promise in enabling intelligent and interactive chatbots for ACP. The present protocol outlines the development and evaluation of a large language model (LLM)-based ACP chatbot for healthcare providers. METHODS AND ANALYSIS: The development of the LLM-based ACP chatbot will follow four stages: construction of dialogue data sets, fine-tuning, multi-LLM orchestration and ablation studies. A randomised controlled trial will then evaluate the LLM-based ACP chatbot's effectiveness in enhancing ACP competence among healthcare providers. A total of 66 healthcare providers will be recruited from China and randomly assigned (1:1) to either: (1) The LLM-based ACP chatbot intervention or (2) An ACP knowledge manual. The primary outcome will be ACP competence, while secondary outcomes will include (1) ACP knowledge, (2) Attitudes/beliefs, (3) Practice willingness, (4) Readiness, (5) Self-efficacy, (6) Processes of change, and (7) Decisional balance. Both primary and secondary outcomes will be assessed to evaluate the immediate impact (postintervention) and short-term impact (3-month follow-up and 6-month follow-up) of the chatbot on ACP. ETHICS AND DISSEMINATION: The research was approved by the Ethical Review Board, Xiangya School of Nursing, Central South University (E202442). Study modifications will be discussed among the research team members until a consensus is reached. Amendments reflecting study modifications will be submitted for institutional review board approval at all sites, updated on the clinical trial registry, and fully detailed and explained in the manuscript reporting the results of the study. All participants will provide written informed consent. The study will be conducted according to the principles outlined in the Declaration of Helsinki. The results of this study will be submitted for publication in peer-reviewed journals and presented at (inter)national conferences. TRIAL REGISTRATION NUMBER: ChiCTR2400091022.

Indexed as

Advance Care PlanningArtificial IntelligenceHealth PersonnelChinaDecision MakingGenerative Artificial IntelligenceHumansLanguageLarge Language ModelsRandomized Controlled Trials as TopicClinical ProtocolsDigital TechnologyMEDICAL EDUCATION & TRAININGPALLIATIVE CARE

Identifiers

PMID41248365
PMCPMC12625866

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.