Evidence map›Paper›PMID 41248362›Full record

ArticleBMJ open2025

Identifying risk factors of long sickness absences: a registry-based study using explainable AI methods.

Anniina Anttila, Mikko Nuutinen, Riikka-Leena Leskelä, Mark van Gils, Riitta Sauni

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anniina Anttila *Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland anniina.anttila@finla.fi.ORCID http://orcid.org/0009-0006-5234-0332
Mikko Nuutinen *Nordic Healthcare Group Oy, Helsinki, Finland.ORCID http://orcid.org/0000-0002-7429-3710
Riikka-Leena LeskeläNordic Healthcare Group Oy, Helsinki, Finland.ORCID http://orcid.org/0000-0002-9255-2958
Mark van GilsFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID http://orcid.org/0000-0002-0029-1771
Riitta SauniFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID http://orcid.org/0000-0002-9808-3638

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify and explore variable groups and individual predictors of long sickness absences outside of well-known predictors such as service use and previous sickness absence using machine learning, explainable artificial intelligence methods and a submodel approach.

designRetrospective study of prospectively collected registry data on sickness absences and a questionnaire used in health examinations.

settingElectronic medical record data of one large occupational health service provider in Finland.

participants11 533 employees of various occupations who, between 2011 and 2019, had at least once completed a health questionnaire that could be linked to service usage data and who had not had their initial health check within 1 year before or 3 months after completing the questionnaire. PRIMARY OUTCOME MEASURES: To identify predictors of at least one long sickness absence period (≥30 days) during a 2-year follow-up.

resultsThe highest area under the receiver operating characteristic curve (AUROC) values among the submodel groups were for the sickness absence and service use submodels (0.68-0.74). The AUROC values for the submodels of sociodemographic factors, health habits or diseases data category ranged from 0.55 to 0.67 and from 0.55 to 0.67 for the submodels of questionnaire data. The AUROC value of the ensemble model that combined all submodels was 0.79 (95% CI 0.788 to 0.794).The most important factors predicting long sickness absences based on the submodels were reported pain, number of symptoms and diseases, body mass index and short sleep duration. Additionally, several work and mental health-related variables increased the risk of long sickness absence.

conclusionsOther variables besides service use and sickness absence increase the accuracy in predicting long sickness absence and providing information for planning interventions that could have a beneficial impact on work disability risk.

Indexed as

AbsenteeismArtificial IntelligenceSick LeaveAdultFemaleFinlandHumansMachine LearningMaleMiddle AgedRegistriesRetrospective StudiesRisk FactorsROC CurveSurveys and QuestionnairesArtificial IntelligenceOccupational Health ServicesPREVENTIVE MEDICINE

Identifiers

PMID41248362
PMCPMC12587995

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.