Evidence map›Paper›PMID 41248167›Full record

ArticlePloS one2025

Investigating the psychometric properties of the Patient Health Questionnaire for Adolescents (PHQ-A) and Center for Epidemiologic Studies - Depression Scale for Children (CES-DC) among young adolescents in South Africa.

Mirriam Mkhize, Claire van der Westhuizen, Katherine Sorsdahl

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mirriam MkhizeAlan J. Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, South Africa.ORCID https://orcid.org/0000-0002-6416-5395
Claire van der WesthuizenAlan J. Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, South Africa.
Katherine SorsdahlAlan J. Flisher Centre for Public Mental Health, Department of Psychiatry and Mental Health, University of Cape Town, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression among adolescents is a global concern, including in South Africa, emphasizing the need for reliable screening tools. While the the Patient Health Questionnaire Adolescent (PHQ-A) and Center for Epidemiologic Studies - Depression Scale for Children (CES-DC) are commonly used mental health screening tools among adolescents, their psychometric properties in South Africa are not well-studied. This study aims to fill this gap by examining the psychometric properties of the PHQ-A and CES-DC among adolescents aged 10-14-year-olds in South Africa. First, a sample of 42 adolescents aged 10-14 years were recruited to participate in cognitive testing focus groups to determine their comprehension of the depression screening tool items. Secondly, a sample of 500 adolescents from 10 schools completed a tablet-based survey including socio-demographic information and the adapted depression screening tools. A subset of 123 adolescents underwent clinical diagnostic interview with the MINI-KID depression modules only. After two weeks, a subset of 145 adolescents had the initial tablet-based survey re-administered for test-retest reliability. Criterion validity was examined using ROC analysis, with the MINI-KID as the reference standard. Of the 500 adolescents surveyed, the majority were female (59.2%), with an average age of 12 years (SD = 1.42). The PHQ-A demonstrated good internal consistency (alpha = 0.82) and moderate test-retest reliability (ICC = 0.56). The CES-DC showed good internal consistency (alpha = 0.86) and moderate test-retest reliability (ICC = 0.68). The PHQ-A displayed good sensitivity (85.7%) and specificity (61.8%). Youden's index indicated 7.5 as the ideal cutoff score for the PHQ-A. The CES-DC has a sensitivity of 95.2% and specificity of 56.9% and Youden's index of 21. Factor structure for the PHQ-A included one factor loading for 9 items and 3 factor loading for 8 items; while for the CES-DC factor structure consisted of o three factor loadings. The findings show good psychometric properties of the PHQ-A and CES-DC and contributes to the limited research on mental health assessment tools for younger adolescents in Africa. Testing the psychometric properties of the PHQ-A and CES-DC for this population could help improve early detection and intervention for mental health conditions.

Indexed as

DepressionPatient Health QuestionnairePsychometricsAdolescentChildFemaleHumansMaleMass ScreeningPsychiatric Status Rating ScalesReproducibility of ResultsSouth AfricaSurveys and Questionnaires

Identifiers

PMID41248167
PMCPMC12622798

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.