Evidence map›Paper›PMID 41247774›Full record

ArticleAlcohol and alcoholism (Oxford, Oxfordshire)2025

Diagnostic validity of alcohol demand and monetary delay discounting in relation to alcohol use disorder.

Peter Najdzionek, Michael Amlung, Lawrence Sweet, James MacKillop

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alcohol and alcoholism (Oxford, Oxfordshire), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Peter NajdzionekDepartment of Psychiatry & Behavioural Neurosciences, McMaster University, 100 West 5th Street, Hamilton, ON L8P 3R2, Canada.ORCID 0000-0001-7982-523X
Michael AmlungDepartment of Applied Behavioral Science, University of Kansas, 1000 Sunnyside Avenue, Lawrence, KS 66045, United States.
Lawrence SweetDepartment of Psychology, University of Georgia, 125 Baldwin Street, Athens, GA 30602, United States.
James MacKillopDepartment of Psychiatry & Behavioural Neurosciences, McMaster University, 100 West 5th Street, Hamilton, ON L8P 3R2, Canada.ORCID 0000-0002-8695-1071

Funding

Using Neuroeconomics to Understand Alcohol Overvaluation in Alcohol Use DisorderR01AA025911 · NIAAA · UNIVERSITY OF GEORGIA · PI MACKILLOP, JAMES, SWEET, LAWRENCE H · 2018 to 2022
$1.3M
Using Neuroeconomics to Characterize State-Based Increases and Decreases in Alcohol ValueR01AA027255 · NIAAA · UNIVERSITY OF KANSAS LAWRENCE · PI AMLUNG, MICHAEL T. · 2019 to 2023
$1.2M
Canada Research Chair in Translational Addiction Research CRC-2020-00170National Institute on Alcohol Abuse and Alcoholism, the Peter Boris Chair in Addictions Research R01 AA027255 (M.A.) and R01 AA025911NIAAA NIH HHS R01 AA025911NIAAA NIH HHS R01 AA027255
6 · The paper itself

Abstract

backgroundA reinforcer pathology approach to alcohol use disorder (AUD) proposes that high alcohol reinforcing value (high alcohol demand) and overvaluation of immediate rewards (high discounting of future rewards) are critical determinants of problematic drinking. Applied to clinical settings, these indicators have not been examined as potential assessments for use in clinical practice. Toward that end, the current study examined whether reinforcer pathology indicators accurately classify individuals with AUD from recreational drinkers without AUD at levels that would meet clinical accuracy benchmarks.

methodsIn a case-control sample of 267 Canadian adults (180 meeting DSM-5 criteria for AUD), receiver operating characteristic (ROC) curves were constructed using reinforcer pathology indicators from an alcohol purchase task and a monetary delay discounting tasks.

resultsAnalysis of the ROC curves revealed that three alcohol demand indices from the alcohol purchase task [i.e. Intensity (observed consumption when free), Omax (observed maximum expenditure), and α (a derived index of price-sensitivity)] significantly differed by groups and met established clinical benchmarks for diagnostic differentiation. While delay discounting significantly differed between groups, it did not meet benchmarks as a clinical differentiator.

conclusionsThis study provides evidence that behavioral economic measures of alcohol valuation accurately diagnostically discriminate individuals with AUD from recreational drinkers. Future work should consider utilizing other behavioral economic indices and validating these results in more diverse populations.

Indexed as

Alcohol DrinkingAlcoholismDelay DiscountingAdultCanadaCase-Control StudiesFemaleHumansMaleMiddle AgedReproducibility of ResultsRewardROC CurveYoung Adultalcohol demandalcohol use disorderclassificationdelay discountingreinforcer pathology

Identifiers

PMID41247774
PMCPMC12622221

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.