Evidence map›Paper›PMID 41247608›Full record

ReviewJournal of epidemiology and global health2025

A Narrative Review of Human Papillomavirus (HPV) Vaccination in Ecuador: A Crisis of Inequity and an Evidence-Based Roadmap for Elimination.

Jose Daniel Sánchez Redrobán, Daniela López, Carlos Santillan

Abstract readReview
In one paragraph

Review in Journal of epidemiology and global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jose Daniel Sánchez RedrobánFacultad de Ciencias de la Salud y Bienestar Humano, Universidad Indoamérica, Quito, Ecuador. danielsanchez@uti.edu.ec.ORCID http://orcid.org/0000-0003-4571-1618
Daniela LópezFacultad de Ciencias de la Salud y Bienestar Humano, Universidad Indoamérica, Quito, Ecuador.
Carlos SantillanFacultad de Ciencias de la Salud y Bienestar Humano, Universidad Indoamérica, Quito, Ecuador.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman Papillomavirus (HPV) remains the leading cause of cervical cancer in Ecuador, which suffers from systemic programmatic failures that undermine the global elimination strategy. CRISIS: Ecuador's HPV vaccination coverage (35.6% first dose; 17.3% complete) is the lowest in Latin America, starkly contrasting with the WHO's 90% target for cervical cancer elimination (Pan American Health Organization 2025). Structural inequities, a profound genotypic mismatch with the circulating quadrivalent vaccine (HPV 58/31/52 prevalence), and fragmented implementation perpetuate this public health crisis (Jose Ortiz Segarra et al. Infectious Disease Reports, 15(3):267-278 2023). KEY

findingsOur analysis reveals that the nation's health-center-based model fails to reach vulnerable populations, a problem exacerbated by critical cold chain deficiencies in 30% of facilities. In contrast, regional successes, such as Peru's school-based programs (94% coverage) and Colombia's strategic adoption of the nonavalent vaccine, offer a clear roadmap for reform (Pan American Health Organization 2025, María Ines Sarmiento-Medina et al. PLOS ONE, 19(2):e0297579 2024). RECOMMENDATIONS: We propose an evidence-based 5-point plan to overhaul Ecuador's strategy: a targeted nonavalent vaccine pilot, immediate adoption of a single-dose schedule, culturally adapted self-sampling programs, phased-in gender-neutral vaccination, and urgent investment in cold chain infrastructure.

Indexed as

Disease EradicationHealthcare DisparitiesImmunization ProgramsPapillomavirus InfectionsPapillomavirus VaccinesUterine Cervical NeoplasmsVaccinationVaccination CoverageEcuadorFemaleHuman Papillomavirus VirusesHumansPapillomavirus VaccinesCervical cancerEcuadorHealth inequalitiesHerd immunityHPVHuman PapillomavirusLatin america.Public healthVaccination coverage

Identifiers

PMID41247608
PMCPMC12623522

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.