Evidence map›Paper›PMID 41247562›Full record

ReviewVeterinary research communications2025

Bridging biology and therapy: translational advances of extracellular vesicles in veterinary clinical practice.

Walaa A Gad, Sally Ibrahim, Hiam Nagdy, Bassma S M Elsawy, Dina Aboelsoued, Hoda S M Abdel-Ghany, Ahmed A A Abdel-Wareth, Khaled A Abd El-Razik, Karima Gh M Mahmoud, Walid T M Soliman and 1 more

Abstract readReview
In one paragraph

Review in Veterinary research communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Walaa A GadDepartment of Animal Reproduction & Artificial Insemination, Veterinary Research Institute, National Research Centre, Giza, Egypt. walaa.gad2018@gmail.com.
Sally IbrahimDepartment of Animal Reproduction & Artificial Insemination, Veterinary Research Institute, National Research Centre, Giza, Egypt.
Hiam NagdyDepartment of Animal Reproduction & Artificial Insemination, Veterinary Research Institute, National Research Centre, Giza, Egypt.
Bassma S M ElsawyDepartment of Parasitology and Animal Diseases, Veterinary Research Institute, National Research Centre, Giza, Egypt.
Dina AboelsouedDepartment of Parasitology and Animal Diseases, Veterinary Research Institute, National Research Centre, Giza, Egypt.
Hoda S M Abdel-GhanyDepartment of Parasitology and Animal Diseases, Veterinary Research Institute, National Research Centre, Giza, Egypt.
Ahmed A A Abdel-WarethDepartment of Animal and Poultry Production, Faculty of Agriculture, South Valley University, Qena, 83523, Egypt.
Khaled A Abd El-RazikDepartment of Animal Reproduction & Artificial Insemination, Veterinary Research Institute, National Research Centre, Giza, Egypt.
Karima Gh M MahmoudDepartment of Animal Reproduction & Artificial Insemination, Veterinary Research Institute, National Research Centre, Giza, Egypt.
Walid T M SolimanDepartment of Development of Animal Wealth, Faculty of Veterinary Medicine, Egyptian Chinese University, Cairo, Egypt.
Mohamed O TaqiCentral Laboratory for Agricultural Climate, Agricultural Research Center, Ministry of Agriculture and Land Reclamation, Dokki, Giza, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are small membrane-bound particles released by numerous cell types and are gaining popularity in veterinary medicine due to their extensive biological activities and therapeutic potential. This review summarizes the classification, biogenesis, and molecular cargo of various types of EVs, such as exosomes, microvesicles, and apoptotic bodies, as well as their emerging roles in cellular communication, diagnostics, and therapeutics across a wide range of veterinary applications. Beyond mesenchymal stem cell (MSC)-derived EVs, EVs from immune cells, pathogens, and body fluids show great promise for tissue healing, immunological regulation, infectious disease management, drug delivery systems, vaccine development, and reproductive health. We critically evaluate recent advancements, limitations, and future possibilities in using EVs to improve diagnosis and treatment results in veterinary species. The review's goal is to provide a comprehensive picture of the rapidly increasing EV landscape and to make it easier to incorporate EV-based technology into clinical veterinary practice.

Indexed as

Extracellular VesiclesVeterinary MedicineAnimalsDrug deliveryEV-based vaccinesExtracellular vesiclesInfectious diseasesReproductive disordersTherapeutic applications

Identifiers

PMID41247562
PMCPMC12628400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.