SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Mind-body interventions for cancer-related dyspnoea: a systematic review and meta-analysis of randomised controlled trials.
Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Dyspnoea is a common and distressing symptom experienced by people with cancer which can impact physical functioning, mental health and quality of life (QoL). Mind-body interventions (MBIs) involving physical and mental practices are based on the belief that movement, cognition and emotions influence physical and spiritual well-being. This review investigated the effect of MBIs on dyspnoea and associated outcomes in people with cancer. Searches were performed using seven different electronic databases for studies published after January 1, 2013, with the keywords combined for cancer, dyspnoea and MBIs. The Risk of Bias 2 (RoB-2) tool was used to assess risk of bias, and data were analysed using Review Manager 5.4. Six randomised controlled trials met the inclusion criteria: three studies investigated qigong, two investigated yoga and one investigated combined breathing and relaxation techniques. Considerable heterogeneity was observed in the outcomes, and one study was classified as high risk of bias. Overall, the meta-analysis showed that MBIs did not improve dyspnoea (SMD = -0.48, 95% CI -1.36 to 0.39, p = 0.28), quality of life (QoL) (SMD = -1.04, 95% CI -3.26 to 1.19, p = 0.36), exercise capacity (SMD = -0.02, 95% CI -0.24 to 0.20, p = 0.87) and anxiety (SMD = -0.68, 95% CI -1.55 to 0.19, p = 0.12). Whilst MBIs did not significantly reduce dyspnoea and anxiety, methodological issues in the six included RCTs may have impacted the studies, and further rigorous studies are required to assess the efficacy of MBIs in this patient population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.