Evidence map›Paper›PMID 41247052›Full record

ArticleMicrobiology spectrum2026

Microbial succession in human tissues postmortem: insights from 2bRAD-M sequencing.

Xin Huang, Jianye Zeng, Fan Yang, Yanan Liu, Ji Chen, Hongyan Wang, Shilin Li, Chengtao Li, Suhua Zhang

Abstract read
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xin Huang *Institute of Forensic Science, Fudan University, Shanghai, People's Republic of China.ORCID 0009-0009-6959-3610
Jianye Zeng *Institute of Forensic Science, Fudan University, Shanghai, People's Republic of China.
Fan YangInstitute of Forensic Science, Shanghai Municipal Public Security Bureau/Key Laboratory of Crime Scene Evidence, Shanghai, People's Republic of China.
Yanan LiuInstitute of Forensic Science, Shanghai Municipal Public Security Bureau/Key Laboratory of Crime Scene Evidence, Shanghai, People's Republic of China.
Ji ChenInstitute of Forensic Science, Fudan University, Shanghai, People's Republic of China.
Hongyan WangThe State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, People's Republic of China.
Shilin LiInstitute of Forensic Science, Fudan University, Shanghai, People's Republic of China.ORCID 0000-0002-2371-938X
Chengtao LiInstitute of Forensic Science, Fudan University, Shanghai, People's Republic of China.ORCID 0000-0001-6852-9144
Suhua ZhangInstitute of Forensic Science, Fudan University, Shanghai, People's Republic of China.ORCID 0000-0002-3984-9728

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial communities play a crucial role in decomposition, yet their patterns in human tissues remain underexplored. Most previous research has often focused on animal models such as mice and swine, with limited studies on human samples, primarily targeting specific environments like the gut and skin. Consequently, gaps persist in understanding postmortem microbial dynamics within internal human organs. The 2bRAD-M sequencing technology offers a powerful approach for human thanatomicrobiome research, overcoming key limitations of 16S rRNA and metagenomic sequencing methods. In this study, we used 2bRAD-M to profile microbial succession across seven human tissues-heart, liver, spleen, lung, kidney, calf muscle, and gut-at various postmortem intervals (PMIs). Significant variations in microbial community composition were observed across organs and decomposition stages, with

Indexed as

BacteriaMicrobiotaPostmortem ChangesCadaverFemaleHumansKidneyLiverLungMaleMetagenomicsRNA, Ribosomal, 16SSpleenRNA, Ribosomal, 16S2bRAD-M sequencingmicrobial successionpostmortem intervalthanatomicrobiome

Identifiers

PMID41247052
PMCPMC12772320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.