Evidence map›Paper›PMID 41246968›Full record

ArticleDermatology reports2026

Syphilis, the great mimicker: an inverted diagnostic pathway that still hits the mark.

Barbara Cocuroccia, Francesca Passarelli, Enzo Palese, Alessandra Latini, Francesca Di Tullio, Filomena Russo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dermatology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Barbara CocurocciaDepartment of Dermatology, Istituto Dermopatico dell'Immacolata IRCCS, Dermatological Research Hospital, Rome.
Francesca PassarelliPathology Unit, Istituto Dermopatico dell'Immacolata IRCCS, Rome.
Enzo PaleseDepartment of Dermatology, Istituto Dermopatico dell'Immacolata IRCCS, Dermatological Research Hospital, Rome.
Alessandra LatiniSexually Transmitted Infections/HIV Unit, San Gallicano Dermatological Institute IRCCS, Rome.
Francesca Di TullioSexually Transmitted Infections/HIV Unit, San Gallicano Dermatological Institute IRCCS, Rome.
Filomena RussoDepartment of Dermatology, Istituto Dermopatico dell'Immacolata IRCCS, Dermatological Research Hospital, Rome.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dear Editor, Syphilis, the "great mimicker", remains a diagnostic challenge despite reliable serologic assays and updated management guidelines. Its wide variety of clinical and dermatological manifestations often leads to misdiagnosis, especially when lesions are atypical. We present a case in which secondary syphilis was diagnosed through an inverted pathway, with histopathology preceding clinical suspicion and serologic confirmation. [...].

Indexed as

differential diagnosisimmunohistochemistryperianal dermatosesSexually transmitted diseasessyphilisTreponema pallidum

Identifiers

PMID41246968
PMCPMC13637453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.