ArticleJournal of the American Heart Association2025
Impact of Left Atrial v-Wave Following Mitral Edge-to-Edge Repair on Survival: The MITRA-PRO Registry.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A Novel Invasive Hemodynamic Parameter (V') to Predict Hemodynamic Response to Mitral Transcatheter Edge-to-Edge Repair.Structural heart : the journal of the Heart Team · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTranscatheter edge-to-edge repair (TEER) for mitral regurgitation has been shown to affect left atrial pressure (LAP). However, the prognostic significance of postprocedural LAP changes remains a matter of debate. We aimed to evaluate the impact of v-wave on long-term survival after TEER.
methodsA total of 1487 patients in the large-scale, multicenter MITRA-PRO (MITRAclip PROgnosis) registry with post-mitral TEER v-wave assessment were included in this study.
resultsAfter 3-years, survival was significantly reduced in patients with increased v-wave after mitral TEER, while patients with decreased v-wave showed the lowest 3-year mortality. A receiver operating characteristic analysis revealed a postprocedural v-wave >25 mm Hg as a relevant predictor of 3-year mortality following mitral TEER. Three-year mortality was significantly lower in patients with a v-wave ≤25 mm Hg indicating a postprocedural v-wave >25 mm Hg as a negative predictor of long-term survival (v-wave ≤25 mm Hg group: 34.2% versus v-wave >25 mm Hg group: 46.8%;
conclusionsA postprocedural v-wave >25 mm Hg is linked to reduced long-term survival. Multimodal residual mitral regurgitation assessment including v-wave supports the interventionalist in TEER guidance and optimizing procedural results aiming for decreasing v-wave to <25 mm Hg. REGISTRATION: URL: https://drks.de/search/en/trial/DRKS00012288; German Clinical Trials Register identifier: DRKS00012288.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.