Evidence map›Paper›PMID 41246759›Full record

ArticleCureus2025

Naloxone Co-prescription in Chronic Opioid Therapy: Benefits, Pitfalls, and Lessons Learned.

Alexander Kim, Scott Weiner

Abstract readEditorial
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alexander KimAnesthesiology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.
Scott WeinerEmergency Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There has been a well-publicized epidemic of lethal and non-lethal prescription opioid overdose in the United States. Significant efforts have been made to alter this trajectory, both at the public health and direct medical care levels. One specific method of harm reduction has been the co-prescription of intranasal naloxone to all patients who are prescribed chronic opioids. In this editorial, we discuss our experience of instituting this quality improvement initiative within a large academic pain management center. After an adverse event of inadvertent administration of intranasal naloxone precipitating opioid withdrawal and emergency evaluation, we learned several lessons. These lessons include cultural sensitivity, being specific on prescription instructions, and how to best discuss naloxone co-prescription with our patients.

Indexed as

chronic opioidsnaloxone educationopioid managementprescription opioid overdose deathsstigma in health care

Identifiers

PMID41246759
PMCPMC12614118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.