Evidence map›Paper›PMID 41246674›Full record

ArticleCureus2025

Refractory Antiphospholipid Syndrome With Thoracic Outlet and Superior Vena Cava Syndromes: A Complex Case of Recurrent Thrombosis.

Talha A Khan, Sam Schick, Jacqueline Figueroa, Jay Swami

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Talha A KhanSurgery, Ross University School of Medicine, Weston, USA.
Sam SchickSurgery, Cleveland Clinic Weston Hospital, Weston, USA.
Jacqueline FigueroaInterventional Radiology, American University of the Caribbean School of Medicine, Cupecoy, SXM.
Jay SwamiInternal Medicine, Ross University School of Medicine, Weston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thoracic outlet syndrome (TOS) and superior vena cava syndrome (SVCS) are rare and debilitating conditions that can cause vascular compression, hypercoagulable states, and central venous obstruction. This is the case of a 39-year-old female with treatment-resistant antiphospholipid syndrome (APS), hereditary angioedema (HAE), and mast cell activation syndrome (MCAS) complicated by SVCS and venous TOS. Her clinical course was further challenged by recurrent venous thromboembolism with treatment failure on multiple direct oral anticoagulants (DOACs), with warfarin being the only effective medication. Furthermore, the patient experienced several thrombotic events, which included: left subclavian vein thrombosis, recurrent deep vein thromboses (DVTs), and septic thrombophlebitis (methicillin-sensitive

Indexed as

antiphospholipid syndromehereditary angioedemamast cell activationsuperior vena cava syndromethoracic outlet syndrome

Identifiers

PMID41246674
PMCPMC12614038

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.