Evidence map›Paper›PMID 41246633›Full record

ReviewCureus2025

Clinical Utility of Contrast-Enhanced Ultrasound (CEUS) in Urology: A Multisystem Review.

Haadia Safdar, Mecaelan Sardar, Niharika Tekchandani, Ahsan Iftikhar, Haider Iftikhar, Faisal Ghumman, Javed Burki

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haadia SafdarUrology, Medway NHS Foundation Trust, Gillingham, GBR.
Mecaelan SardarMedical Education and Simulation, Medway NHS Foundation Trust, Gillingham, GBR.
Niharika TekchandaniHospital Medicine, Medway NHS Foundation Trust, Gillingham, GBR.
Ahsan IftikharMedicine, City St. Georges University of London, London, GBR.
Haider IftikharHospital Medicine, Army Medical College, Rawalpindi, Rawalpindi, PAK.
Faisal GhummanUrology, Medway NHS Foundation Trust, Gillingham, GBR.
Javed BurkiUrology, Medway NHS Foundation Trust, Gillingham, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contrast-enhanced ultrasound (CEUS) is a non-invasive, versatile imaging technique with an expanding spectrum of uses across a wide variety of urological disorders. By utilizing microbubble-based contrast agents confined to the intravascular space, CEUS provides real-time, high-resolution assessment of tissue vascularity without ionizing radiation or nephrotoxic contrast. This review presents an updated overview of CEUS applications in urology, including renal mass characterization, staging of bladder cancer, assessment of scrotal trauma, fertility interventions such as microdissection testicular sperm extraction (M-TESE), and adjunctive prostate cancer imaging. Despite multiple advantages, the more widespread use of CEUS is limited by its limited availability and the absence of standardized imaging protocols. As evidence becomes increasingly available and consensus guidelines emerge, CEUS will take its place as a fundamental tool in the diagnostic armamentarium of modern urological practice.

Indexed as

article reviewceuscontrast-enhanced ultrasoundurological pathologyuro-radiology

Identifiers

PMID41246633
PMCPMC12618943

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.