Evidence map›Paper›PMID 41246625›Full record

ReviewCureus2025

The Median Palatine Suture: A Comprehensive Review With Clinical Considerations.

Emma R Lesser, Shogo Kikuta, Blair M Barton, Rarinthorn Samrid, Hotaka Kawai, R Shane Tubbs, Joe Iwanaga

Abstract readReview
In one paragraph

Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emma R LesserDepartment of Neurosurgery, Clinical Neuroscience Research Center, Tulane University School of Medicine, New Orleans, USA.
Shogo KikutaDepartment of Surgery, Dental and Oral Medical Center, Kurume University School of Medicine, Kurume, JPN.
Blair M BartonDepartment of Otorhinolaryngology, Ochsner Health System, New Orleans, USA.
Rarinthorn SamridDepartment of Anatomy, Khon Kaen University, Khon Kaen, THA.
Hotaka KawaiDepartment of Oral Pathology and Medicine, Okayama University, Okayama, JPN.
R Shane TubbsDepartment of Neurosurgery, Clinical Neuroscience Research Center, Tulane University School of Medicine, New Orleans, USA.
Joe IwanagaDepartment of Neurosurgery, Clinical Neuroscience Research Center, Tulane University School of Medicine, New Orleans, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The median palatine suture (MPS) is an articulation in the midsagittal plane in the oral cavity's roof that divides the palate into two halves. Its anterior and posterior segments are formed by the fusion of the maxillary palatine processes and the horizontal plates of the palatine bones, respectively. This review synthesizes the classical understanding of the MPS with recent multidisciplinary advancements to provide a contemporary and holistic perspective. We delve into its comparative anatomy and evolutionary origins, and further detail the molecular and cellular mechanisms governing its development, maturation, and response to mechanical force. The discussion extends to modern imaging modalities for assessing sutural patency and maturation, encompassing cone-beam computed tomography (CBCT), magnetic resonance imaging (MRI), and the application of artificial intelligence (AI) for automated analysis. Clinically, the MPS is significant across diverse fields; its role is discussed in the context of pathology, such as cleft palate, its utility in forensic age estimation, and its central importance in contemporary orthodontic and surgical interventions, notably microimplant-assisted rapid palatal expansion (MARPE). By consolidating the current state of knowledge and identifying key directions for future research, this review serves as an essential resource for clinicians and researchers engaged in maxillofacial surgery, orthodontics, and forensic science.

Indexed as

anatomycleft palatecomparative anatomycranial suturesembryologyforensic age assessmentpalate

Identifiers

PMID41246625
PMCPMC12619025

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.