Evidence map›Paper›PMID 41246607›Full record

ArticleCureus2025

Painless Aortic Dissection With Bradycardia, Hypotension, and Lower Limb Weakness: A Case Report.

Kaho Sakurai, Ryoichi Inoue, Toshinori Nishizawa

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kaho SakuraiEmergency Department, Yokosuka General Medical Center, Yokosuka, JPN.
Ryoichi InoueInternal Medicine, The Ohio State University Wexner Medical Center, Columbus, USA.
Toshinori NishizawaGeneral Internal Medicine, St. Luke's International Hospital, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aortic dissection typically presents with chest or back pain, but it can be painless. In the absence of typical pain, diagnosis may be delayed or missed. We present a case of an 84-year-old woman in which the initial manifestations were transient bilateral lower-limb weakness accompanied by bradycardia and hypotension. Electrocardiography demonstrated marked sinus bradycardia without ischemic changes, and laboratory tests were unremarkable except for an elevated D-dimer. Bedside carotid duplex ultrasonography incidentally identified an intimal flap in the common carotid artery, and contrast-enhanced computed tomography (CECT) confirmed Stanford type A aortic dissection involving the aortic arch with extension into both common carotid arteries. The patient underwent emergent valve-sparing supracoronary ascending aortic replacement. This case underscores the importance of recognizing unexplained bradycardia, hypotension, and transient muscle weakness as early clues to painless aortic dissection. Carotid duplex ultrasonography may aid diagnosis in such atypical presentations and should be considered when standard evaluations are inconclusive, potentially reducing missed or delayed diagnoses.

Indexed as

aortic dissectionbradycardiacarotid ultrasoundhypotensionneurological symptomspainless presentation

Identifiers

PMID41246607
PMCPMC12612959

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.