Evidence map›Paper›PMID 41246574›Full record

ArticleCureus2025

Unraveling Peritoneal Mesothelioma: A Case-Based Discussion on Diagnosis and Management.

Othmane Zouiten, Latifa Azarou, Hasnaa Hadiri, Hanane Rais, Rhizlane Belbaraka

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Othmane ZouitenDepartment of Medical Oncology, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital of Marrakech, Cadi Ayyad University, Marrakech, MAR.
Latifa AzarouDepartment of Medical Oncology, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital of Marrakech, Cadi Ayyad University, Marrakech, MAR.
Hasnaa HadiriDepartment of Pathology, Mohammed VI University Hospital of Marrakech, Cadi Ayyad University, Marrakech, MAR.
Hanane RaisDepartment of Pathology, Mohammed VI University Hospital of Marrakech, Cadi Ayyad University, Marrakech, MAR.
Rhizlane BelbarakaDepartment of Medical Oncology, University Hospital of Marrakesh, Marrakesh, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peritoneal mesothelioma is a rare and aggressive tumor, and its management remains poorly standardized in the literature. This case highlights the diagnostic and therapeutic challenges through a 56-year-old woman with no significant medical history or known asbestos exposure, who presented with progressive abdominal distension and postprandial vomiting. Imaging revealed diffuse nodular peritoneal thickening and large-volume ascites. A laparoscopic biopsy confirmed malignant epithelioid mesothelioma, supported by immunohistochemical positivity for cytokeratin 7 (CK7), calretinin, and Wilms tumor 1 (WT1). Treatment was based on systemic chemotherapy with platinum (cisplatin/carboplatin) and pemetrexed, which elicited a rapid initial response. However, the long-term efficacy remains uncertain due to the aggressive nature of the disease. The absence of standardized treatment underscores the necessity for multidisciplinary management.

Indexed as

cytoreductive surgeryepithelioid subtypeimmunohistochemistry (ihc)peritoneal mesotheliomasystemic chemotherapy

Identifiers

PMID41246574
PMCPMC12617991

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.