Evidence map›Paper›PMID 41246478›Full record

Trial reportClinical interventions in aging2025

Effects of Multicomponent Otago Exercise Program with Added Resistance Training on Sarcopenia in Pre-Frailty Older Adults in Nursing Homes: A Randomized Controlled Trial.

Neng Pan, Yan Chen, Zhaojian Wang, Chenming Liu, Jun Tong, Yuchen He, Zbigniew Marcin Ossowski

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical interventions in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Neng PanFaculty of Physical Culture, Gdansk University of Physical Education and Sport, Gdansk, Poland.
Yan ChenSports Department, Northwest A&F University, Yanglin, Shanxi, People's Republic of China.
Zhaojian WangSports Department, Yunnan Normal University, Kunming, Yunnan, People's Republic of China.
Chenming LiuDepartment of Sports Training, Chendu Sport University, Chendu, Sichuan, People's Republic of China.
Jun TongSports Department, Kunming Medical University, Kunming, Yunnan, People's Republic of China.
Yuchen HeSports Department, Capital University of Physical Education and Sports, Beijing, People's Republic of China.
Zbigniew Marcin OssowskiFaculty of Physical Culture, Gdansk University of Physical Education and Sport, Gdansk, Poland.ORCID 0000-0002-3226-2430

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Otago Exercise Program (OEP) is suitable for frail older adults but has limited effect on sarcopenia. Resistance training (RT) is commonly used for sarcopenia. This study evaluated the effects of 12 weeks of OEP combined with RT on body composition, physical function, quality of life, and frailty in older adults with pre-sarcopenia in nursing homes. Methods: Sixty-one pre-frail elderly (aged 65-89 years) with sarcopenia were randomly divided into experimental group (EG) and control group (CG). EG received OEP+RT training three times a week for 12 weeks, and CG maintained daily activities. The InBody 770 was used to assess body composition, Jamar Plus was used to measure grip strength, and international standard scales were used to assess physical function, quality of life and frailty. Results: Compared to the CG, the EG showed significant improvements in Skeletal Muscle Index (SMI: 5.79 vs 5.43, p=0.037), Skeletal Muscle Mass (21.8 vs 19.5, p=0.017), hand grip strength (19.31 vs 16.92, p=0.029), gait speed (0.9 vs 0.81, p<0.001), and the Five-Times-Sit-to-Stand Test (13 vs 14.35, p<0.001). Within the EG, both SMI and hand grip strength increased significantly compared to baseline levels (p<0.001), whereas in the CG, they decreased significantly (p<0.05). There was no significant improvement in frailty status observed in either group. Conclusion: OEP combined with RT can improve the sarcopenia-related parameters of the elderly in nursing homes. Short-term unreversed frailty may be related to insufficient intervention intensity or single dimension. Improved muscle and physical function may contribute to future improvements in quality of life and frailty.

Indexed as

Exercise TherapyResistance TrainingSarcopeniaActivities of Daily LivingAgedAged, 80 and overBody CompositionFemaleFrail ElderlyFrailtyHand StrengthHumansMaleMuscle, SkeletalNursing HomesQuality of Lifemulticomponent exercisenursing homesolder adultsOtago Exercise Programpre-frailtysarcopenia

Identifiers

PMID41246478
PMCPMC12619544

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.