Evidence map›Paper›PMID 41246463›Full record

ArticleIJTLD open2025

Post-TB treatment completion experiences of children, adolescents, and caregivers from Cape Town.

C Monin, D T Wademan, C Purdy, M Mlomzale, M G Anthony, T Cousins, L Viljoen, J Orne-Gliemann, M M van der Zalm, G Hoddinott

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in IJTLD open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

C MoninDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.
D T WademanDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.
C PurdyDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.
M MlomzaleDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.
M G AnthonyDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.
T CousinsOxford School of Anthropology and Museum Ethnography, University of Oxford, Oxford, UK.
L ViljoenDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.
J Orne-GliemannNational Institute for Health and Medical Research (INSERM), UMR 1219, Research Institute for Sustainable Development (IRD), EMR 271, Bordeaux Population Health Centre, University of Bordeaux, Bordeaux, France.
M M van der ZalmDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.
G HoddinottDesmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.

Funding

The long-term consequences of pulmonary tuberculosis and respiratory viruses on lung health in young South African childrenK43TW011028 · FIC · STELLENBOSCH UNIVERSITY · PI VAN DER ZALM, MARIEKE MARGREET · 2020 to 2024
$647k
FIC NIH HHS K43 TW011028
6 · The paper itself

Abstract

backgroundPost-TB life is associated with a range of clinical, economic, social, and psychological sequelae, with limited data available on children and adolescents. We describe child TB survivors' physical, emotional, and social post-TB treatment experiences, in a high-incidence setting in South Africa.

methodsAn explorative qualitative study was nested within the Umoya TB cohort between June and September 2023. We used semi-structured interviews and participatory methods, including body mapping, to explore participants' physical, emotional, and social wellbeing. Data were analysed using a deductive thematic approach and a health-related quality-of-life framework.

resultsThirty semi-structured interviews were conducted with 15 children/adolescents; median age 9 years (range: 5-15); 8 (53%) were male; 2 (13%) living with HIV, and 1 (6%) had multidrug-resistant TB. Most interviews were conducted with children together with their caregivers (N = 14). Interviews were done 11-61 months (41-month average) after TB treatment completion. All participants reported that TB significantly impacted their physical, psychological, and social domains, extending well beyond treatment completion. Children and adolescents perceived changes in their bodies like shortness of breath and physical pain following their TB episode, reporting various physical post-TB cure symptoms. TB-related stigma disrupted participants' social relationships, especially among adolescents. Broader underlying socio-environmental challenges exacerbated the long-term economic impact of TB on household financial instability.

conclusionThe negative impacts of TB extend well beyond children and adolescents' treatment completion across multiple aspects of their lives. Future studies should prioritise the development of interventions to enhance communication and optimise follow-up care for paediatric TB survivors.

Indexed as

Cape Townhealth-related quality of lifeHRQoLPTLDSouth Africatuberculosis

Identifiers

PMID41246463
PMCPMC12617085

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.