ArticleOpen veterinary journal2025
Comparison of normal adiponectin levels among animal population: Prospective health and metabolic physiology.
Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Background: Public health in animals is increasingly being recognized due to its role in elucidating metabolic and physiological disorders in different species. Adiponectin, a hormone secreted by adipocytes, is a significant marker of glucose and lipid metabolism and metabolic health. However, baseline serum adiponectin levels in different animal species are not well characterized. Aim: This study aimed to measure and compare baseline serum adiponectin levels among nine animal species as a reference for physiological and metabolic investigations in veterinary science. Methods: We analyzed 90 sera samples (10/species) from healthy fish, chicken, rabbit, cat, dog, goat, sheep, cow, and rat. Adiponectin levels were assessed using a validated enzyme-linked immunosorbent assay-based method. Results: Large interspecies differences were observed. The highest adiponectin levels were found in rats (7.22 ± 0.25 ng/ml), followed by cows (6.94 ± 0.23 ng/ml) and goats (6.35 ± 0.25 ng/ml). Adiponectin levels were lower in rabbits (3.89 ± 0.18 ng/ml), chickens (2.43 ± 0.17 ng/ml), and fish (1.62 ± 0.11 ng/ml). Conclusion: These findings highlight the role of species-specific metabolic adaptations in adiponectin secretion, with higher levels in mammals overall. This information provides a foundation for future research into metabolic health, animal husbandry, and the physiological functions of adiponectin.
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