Evidence map›Paper›PMID 41246404›Full record

ArticleOpen veterinary journal2025

Effects of boiled fenugreek seed extract on testicular histology and reproductive parameters in adult male mice.

Samira Musa Sasi, Nagia Musa Alghoul, Ragil Angga Prastiya, Khalid Salem

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PubMed Full text at PMC Publisher
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samira Musa SasiDepartment of Zoology, Faculty of Science, University of Tripoli, Tripoli. Libya.
Nagia Musa AlghoulLibyan Center of Biotechnology Researches, Tripoli, Libya.
Ragil Angga PrastiyaFaculty of Health, Medicine and Life Sciences (FIKKIA), Universitas Airlangga, Indonesia.
Khalid SalemDepartment of Plant Biotechnology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fenugreek is a medicinal plant widely used in food and traditional medicine in several countries, including Libya. Aim: This study aimed to evaluate the effects of boiled aqueous fenugreek seed extract on sperm parameters, testicular histology, and embryo morphology in male mice. Method: Adult male mice were randomly divided into three groups ( Results: A significant decrease in body weight was observed in the 1,000 mg/kg treated group. However, no significant differences in testis weight, testosterone levels, sperm motility, or morphology were detected between the treated and control groups. Histological examination revealed no pathological changes in the testicular tissues. In addition, embryos sired by treated males showed no external abnormalities or significant differences in body or tail length compared with controls. Conclusion: Boiled aqueous fenugreek seed extract at doses of 1,000 and 2,000 mg/kg did not exert adverse effects on male reproductive parameters or embryo morphology. Further studies are recommended to evaluate its safety on other body organs and its potential therapeutic applications.

Indexed as

Plant ExtractsReproductionTestisTrigonellaAnimalsMaleMiceSeedsSpermatozoaSperm MotilityTestosteronePlant ExtractsTestosteroneEmbryo morphologyMale miceSperm parametersTestesTrigonella foenum-graecum

Identifiers

PMID41246404
PMCPMC12613225

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.