Evidence map›Paper›PMID 41246386›Full record

ArticleOpen veterinary journal2025

Combined ophthalmic therapy and equine placental extract supplementation to treat corneal perforation in geriatric cats: A case report in the absence of surgical intervention.

Takae Natori, Eiichi Hirano

Abstract readCase Reports
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Takae NatoriIkeda Animal Hospital, Kawasaki, Japan.
Eiichi HiranoMedical Affairs Department, Japan Bio Products Co., Ltd., Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Environmental changes affecting pet animals, along with an increase in age-related conditions and diseases among pets, have become increasingly evident. Despite this trend, there remains a paucity of research on therapeutic approaches for geriatric companion animals. Case Description: The case report describes a 19-year-old spayed female cat that was diagnosed with chronic renal failure and recurrent corneal disease. Surgical intervention was not pursued at the owner's request, leaving medical management as the only viable option. The patient's corneal condition deteriorated, culminating in corneal perforation. Upon initiation of equine placental extract supplementation alongside medical treatment, substantial improvements were observed in hyperaemia, ocular discomfort, and additional corneal manifestations, including wound severity, ocular discharge, photophobia, lacrimation, and blepharospasm. Conclusion: The integration of medical therapy with placental extract supplementation may represent a novel therapeutic alternative for geriatric cats ineligible for surgical intervention.

Indexed as

Cat DiseasesCorneal PerforationPlacental ExtractsAnimalsCatsFemaleHorsesPlacental ExtractsCorneal perforationGeriatric catPlacental extractSupplementation

Identifiers

PMID41246386
PMCPMC12613222

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.