Evidence map›Paper›PMID 41246335›Full record

ReviewFrontiers in immunology2025

Breaking the bind: PfEMP1-specific antibodies in cerebral malaria.

Josephine P Banda, Isobel S Walker, Tonney Nyirenda, Elizabeth H Aitken, Stephen J Rogerson

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Josephine P BandaDepartment of Pathology, Kamuzu University of Health Sciences, Blantyre, Malawi.
Isobel S WalkerDepartment of Infectious Diseases, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, Australia.
Tonney NyirendaDepartment of Pathology, Kamuzu University of Health Sciences, Blantyre, Malawi.
Elizabeth H AitkenDepartment of Infectious Diseases, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, Australia.
Stephen J RogersonDepartment of Infectious Diseases, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC, Australia.

Funding

Identifying functional antibody responses that protect against malaria in childrenR01AI165595 · NIAID · MICHIGAN STATE UNIVERSITY · PI Karl Boynton Seydel · 2022 to 2026
$2.3M
NIAID NIH HHS R01 AI165595
6 · The paper itself

Abstract

Antibodies against

Indexed as

Antibodies, ProtozoanMalaria, CerebralMalaria, FalciparumPlasmodium falciparumProtozoan ProteinsAnimalsAntigens, ProtozoanErythrocytesHumansProtein BindingAntibodies, ProtozoanAntigens, Protozoanerythrocyte membrane protein 1, Plasmodium falciparumProtozoan Proteinsantibodiescerebral malaria (CM)naturally acquired immunityPlasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1)severe malaria (SM)

Identifiers

PMID41246335
PMCPMC12611861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.